CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD141
Family Name Mitogen-activated protein kinase 12 Inhibitor SCIO-469 Family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00138383 Functional Category Clinical Trial Drug with Natural Product
Superfamily Prostaglandin G/H synthase inhibitor salicylates and derivatives Superfamily
Class Class 121

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Danthron family 11 141
Agrimophol family 10 22
Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family 3 11
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 2 19
Steryl-sulfatase Inhibitor Sulfamic Acid 3-(4-hydroxy-benzoyl)... 3 2
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
L-selectin and P-selectin Inhibitor 2,3,4-trihydroxybenzoic Ac... 2 10
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Indoleamine 2,3-dioxygenase 1 Inhibitor Garveatin E Family 2 0
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-622444 Family 2 18
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Aromatase inhibitor (3R,4R)-4-benzyl-3-[(3-hydroxyphenyl)methy... 1 10
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
Thromboxane A2 receptor ligand AGN-PC-003UTI family 1 0
Steryl-sulfatase inhibitor (8R,9S,13S,14S,17R)-17-benzyl-3,17-... 1 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 2
Sterol O-acyltransferase 1 and Sterol O-acyltransferase 2 inhi... 1 5
Benzofurans Metabolite 4-Hydroxyphthalide Family 1 1
Putative NP ZINC49600254 Family 8 2
2,4-diacetyl-5-hydroxy-3-(4-hydroxyphenyl)-5-methylcyclohexen-... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00138383 DCL000226 Clinical Trial Drug SCIO-469

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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