CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Neuromedin-K receptor Ligand Talnetant Family
No. of Seeds 3 No. of Other Members 49
Family Centroid CFAMM00139315 Functional Category Clinical Trial Drug
Superfamily Neuromedin-K receptor Ligand Talnetant Superfamily
Class Class 297

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Neuromedin-K receptor and Substance-K receptor ligand 2-[2-phe... 2 2
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 1 7
NS5B protein inhibitor AC1NQMYG family 6 12
Vascular endothelial growth factor receptor 2 ligand AGN-PC-05... 2 2
Insulin-like growth factor-binding protein 4 and Insulin-like ... 4 44
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C9 liga... 2 6
Plasmepsin-2 and Cathepsin D inhibitor N'-(3,4-dimethylacridin... 1 3
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Type-1B angiotensin II receptor ligand AGN-PC-040VXR family 6 15
Prelamin-A/C and Bloom syndrome protein inhibitor 7-Chlorokynu... 1 10
Cholecystokinin receptor type A ligand (4R)-5-(dipentylamino)-... 1 11
Cysteinyl leukotriene receptor 1 ligand 6-bromo-4-oxo-3-(quino... 3 1
Integrase inhibitor AC1LARQ6 family 1 2
Thrombopoietin receptor ligand AGN-PC-077M9L family 2 4
ATP-dependent molecular chaperone HSP82 and Arachidonate 12-li... 1 2
Streptokinase A and Nuclear receptor ROR-gamma ligand N-[(2,4-... 4 0
Integrase inhibitor AGN-PC-00F9UX family 1 0
Integrase and Serine/threonine-protein kinase pim-1 inhibitor ... 3 0
Serine/threonine-protein kinase pim-1 and Dual specificity tyr... 2 0
NP 8-hydroxyquinoline-2-carbaldehyde Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00139314 CHEMBL219648 Bioactive SureCN9501979
CFAMM00139315 DCL000241 Clinical Trial Drug Talnetant
CFAMM00139303 DNC007029 Investigative Drug 3-hydroxy-2-phenylquinoline-4-carboxylic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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