CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Toll-like receptor 9 Ligand TLR9 Agonist Family
No. of Seeds 8 No. of Other Members 8
Family Centroid CFAMM00140036 Functional Category Clinical Trial Drug with Natural Product
Superfamily Toll-like receptor 9 and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 78

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Yohimbine Family 7 52
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
Melanin-concentrating hormone receptor 1 Ligand Amg 076 Family 2 8
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 4
Neuronal acetylcholine receptor subunit beta-4 Ligand 18-metho... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 4
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 10 9
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 4 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 48


External ID

Functional Category

Molecule Name

CFAMM00140036 DCL000249 Clinical Trial Drug TLR9 agonist
CFAMM00140028 DNC003623 Investigative Drug 2-Hydroxyethyl 18-methoxycoronaridinate
CFAMM00140027 DNC003621 Investigative Drug 15-nor-18-Methoxycornaridine
CFAMM00140037 DNC003631 Investigative Drug N,N-Dimethylaminoethyl 18-methoxycoronaridinate
CFAMM00140026 DNC003627 Investigative Drug 18-Dimethylaminocoronaridine
CFAMM00140035 DNC003615 Investigative Drug 2-Methoxyethyl 18-methoxycoronaridinate
CFAMM00140034 DNC003614 Investigative Drug 18-Methylaminocoronaridine
CFAMM00140023 DNC014491 Investigative Drug CORONARIDINE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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