CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Aldose reductase Inhibitor Sorbinil Family
No. of Seeds 3 No. of Other Members 23
Family Centroid CFAMM00141173 Functional Category Clinical Trial Drug with Natural Product
Superfamily Aldose reductase Inhibitor Sorbinil Superfamily
Class Class 941

Cousin Family NamesSeedsMembers
Aldose reductase inhibitor AGN-PC-00PQ2H family 2 1
Aldose reductase inhibitor AGN-PC-00OGZI family 1 0
Beta-lactamase and Inositol monophosphatase 1 inhibitor T66475... 1 1
NP (s)-n-(3-methoxybenzyl)-3-(1-((4-(4-methoxyphenyl)tetrahydr... 5 0


External ID

Functional Category

Molecule Name

CFAMM00141173 DCL000270 Clinical Trial Drug Sorbinil
CFAMM00141178 DCL000311 Clinical Trial Drug Fidarestat
CFAMM00141165 DNC002722 Investigative Drug Fidarestat(Stereoisomer)

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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