CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name C-C chemokine receptor type 5 Ligand Vicriviroc Family
No. of Seeds 4 No. of Other Members 31
Family Centroid CFAMM00141403 Functional Category Clinical Trial Drug
Superfamily C-C chemokine receptor type 5 Ligand Vicriviroc Superfamily
Class Class 824

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
C-C chemokine receptor type 5 ligand [3-[2-[(3aS,6aR)-5-(4,6-d... 3 40
Substance-P receptor ligand (3R,4S)-N-[[3,5-bis(trifluoromethy... 3 7
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
C-C chemokine receptor type 5 ligand AC1NUXE1 family 12 7
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
C-C chemokine receptor type 5 ligand SureCN3684128 family 2 2
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 3 0
Substance-P receptor ligand 2-[3,5-bis(trifluoromethyl)phenyl]... 3 1
Substance-P receptor ligand Netupitant family 5 2
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
C-C chemokine receptor type 5 ligand N-[3-[4-[3-cyclohexyl-5-(... 5 4
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 2
C-C chemokine receptor type 5 ligand AC1MHPAK family 5 1
C-C motif chemokine 5 inhibitor [(3aS,6aR)-2-[3-(1-cyclopentyl... 3 0


External ID

Functional Category

Molecule Name

CFAMM00141421 CHEMBL1688240 Bioactive SureCN3686629
CFAMM00141419 CHEMBL1688242 Bioactive (4,6-dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R,2R)-2-methoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone
CFAMM00141403 DCL000274 Clinical Trial Drug Vicriviroc
CFAMM00141395 DCL000300 Clinical Trial Drug INCB9471

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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