CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD18
Family Name Histamine H3 receptor Ligand ABT-239 Family
No. of Seeds 8 No. of Other Members 20
Family Centroid CFAMM00127764 Functional Category Clinical Trial Drug
Superfamily adrenergic receptor Ligand Befunolol Hci Superfamily
Class Class 769

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
Histamine H3 receptor Ligand A-349821 Family 49 228
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 4 18
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
Histamine H3 receptor ligand SureCN2786002 family 8 3
Histamine H3 receptor ligand SureCN2785624 family 2 0
Histamine H3 receptor ligand SureCN2784769 family 12 2
Histamine H3 receptor ligand SureCN2785131 family 7 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase and Sigma no... 2 4
Histamine H3 receptor ligand 2-(3,3-difluoropyrrolidin-1-yl)-1... 2 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 3 9
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Multidrug resistance protein 1 inhibitor 1-[4-[(2R)-2-hydroxy-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00127783 CHEMBL180368 Bioactive SureCN2784873
CFAMM00127789 CHEMBL160113 Bioactive SureCN2786122
CFAMM00127775 CHEMBL180125 Bioactive SureCN2784890
CFAMM00127781 CHEMBL161624 Bioactive AGN-PC-03N72S
CFAMM00127787 CHEMBL161781 Bioactive SureCN2786095
CFAMM00127773 CHEMBL161796 Bioactive SureCN2785680
CFAMM00127761 CHEMBL351231 Bioactive ABT-239
CFAMM00127764 DCL000028 Clinical Trial Drug ABT-239

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543