CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Calcium-activated potassium channel subunit alpha-1 Ligand ICA-17043 Family
No. of Seeds 14 No. of Other Members 14
Family Centroid CFAMM00141500 Functional Category Clinical Trial Drug
Superfamily Calcium-activated potassium channel subunit alpha-1 Ligand ICA-17043 Superfamily
Class Class 196

Cousin Family NamesSeedsMembers
Opioid receptor Ligand Methadone Family 3 39
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 5 30
Histone deacetylase Inhibitor CG-1521 Family 2 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-bi... 5 14
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 5-(4... 2 3
Histone deacetylase 1 Inhibitor N-hydroxy-6-oxo-6-phenylhexana... 7 7
Histone deacetylase 1 Inhibitor N-hydroxy-8-(naphthalen-2-yl)n... 6 3
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-2-nap... 3 3
Botulinum neurotoxin type A inhibitor 2-[3-(4-bromophenyl)-1-a... 1 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 0


External ID

Functional Category

Molecule Name

CFAMM00141500 DCL000276 Clinical Trial Drug ICA-17043
CFAMM00141515 DNC008279 Investigative Drug 4-fluorophenyl-2,2-diphenylacetamide
CFAMM00141488 DNC008286 Investigative Drug bis(4-fluorophenyl)-2-fluorophenylacetamide
CFAMM00141497 DNC009952 Investigative Drug N-hydroxy-2,2-diphenylpropanamide
CFAMM00141520 DNC009949 Investigative Drug 2,2-bis(4-fluorophenyl)-N-hydroxyacetamide
CFAMM00141495 DNC008281 Investigative Drug 2,2,2-tris-(3-fluorophenyl)-acetamide
CFAMM00141492 DNC008282 Investigative Drug 2,2-bis-(2-fluorophenyl)-2-phenylacetamide
CFAMM00141509 DNC008277 Investigative Drug (2-fluorophenyl)-(4-fluorophenyl)phenylacetamide
CFAMM00141519 DNC009948 Investigative Drug 2,2-bis(3-fluorophenyl)-N-hydroxyacetamide
CFAMM00141494 DNC008280 Investigative Drug 2-fluorophenyl-2,2-diphenylacetamide
CFAMM00141491 DNC008285 Investigative Drug 2-(3,4-Difluorophenyl)-2,2-diphenylacetamide
CFAMM00141516 DNC008278 Investigative Drug 2,2-bis-(3-fluorophenyl)-2-phenylacetamide
CFAMM00141493 DNC008283 Investigative Drug 2,2,2-tris-(4-fluorophenyl)-acetamide
CFAMM00141490 DNC008284 Investigative Drug 2-(2,4-difluorophenyl)-2,2-diphenylacetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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