CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD182
Family Name Retinoic acid receptor alpha Ligand LG100268 Family
No. of Seeds 2 No. of Other Members 33
Family Centroid CFAMM00141538 Functional Category Clinical Trial Drug
Superfamily Retinoic acid receptor alpha Ligand LG100268 Superfamily
Class Class 946

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Montelukast Family 37 29
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Diacylglycerol O-acyltransferase 2 and Hydroxycarboxylic acid ... 4 45
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Dipeptidyl peptidase 4 Inhibitor TAK-100 Family 5 7
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Transient receptor potential cation channel subfamily V member... 6 23
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Egl nine homolog 2 Inhibitor Pyridine-2,4-dicarboxylic Acid Fa... 2 21
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Isoqui... 1 6
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Metabotropic glutamate receptor 5 Ligand 6-phenylethynyl-nicot... 2 26
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Adenosine receptor A3 and Adenosine receptor A1 ligand propyl ... 6 63
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 4 7
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor AG... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 5
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C9 liga... 2 6
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 5
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 1 1
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 0
ATP-sensitive inward rectifier potassium channel 11 ligand N-[... 1 1
Glycine receptor subunit alpha-1 ligand [(1R,5R)-8-azabicyclo[... 2 10
Transmembrane prolyl 4-hydroxylase inhibitor 2,2'-Bipyridine-5... 1 1
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate N... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00141544 CHEMBL109117 Bioactive SureCN726852
CFAMM00141538 DCL000277 Clinical Trial Drug LG100268

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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