CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD189
Family Name Adenosine receptor A2a Ligand Atl-146e Family
No. of Seeds 33 No. of Other Members 94
Family Centroid CFAMM00141785 Functional Category Clinical Trial Drug
Superfamily Adenosine receptor A2a Binder Superfamily
Class Class 172

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
DNA Binder purine nucleoside Adenosine analog Nelarabine Family 2 10
Bucladesine family 1 1
P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
TG-C family 11 208
Histamine N-methyltransferase Inhibitor S-adenosyl-l-homocyste... 2 3
Adenosylhomocysteinase Inhibitor D-eritadenine Family 2 1
Adenosylhomocysteinase Inhibitor 4(z)-(5'-deoxyadenosin-5'-yli... 2 1
cAMP-dependent protein kinase type I-alpha regulatory subunit ... 12 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 16 6
Adenosine receptor A1 ligand CHEMBL2112106 family 7 7
Adenosine receptor A1 and Adenosine receptor A2a ligand (1S,3S... 3 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 10
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 9 0
Adenosylhomocysteinase and Adenosine deaminase inhibitor AGN-P... 2 1
Adenosine receptor A2a and Adenosine receptor A2b ligand Cgs-2... 1 2
Adenosine receptor A1 ligand CHEMBL411245 family 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand 3-[6-... 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand (3R,4... 7 3
Adenosine receptor A2a and Adenosine receptor A1 ligand (2S,3S... 1 0
Putative Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-di... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00141831 CHEMBL204520 Bioactive (2S,3S,4R,5R)-5-[2-dec-1-ynyl-6-(ethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141877 CHEMBL604207 Bioactive (2S,3S,4R)-5-[6-(cyclohexylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141793 CHEMBL208238 Bioactive (2S,3S,4R,5R)-N-ethyl-5-[6-(ethylamino)-2-[(3R)-3-hydroxyoct-1-ynyl]purin-9-yl]-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141870 CHEMBL609487 Bioactive (2S,3S,4R)-N-(8-acetamidooctyl)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141813 CHEMBL205788 Bioactive (2S,3S,4R,5R)-N-ethyl-5-[6-(ethylamino)-2-oct-1-ynylpurin-9-yl]-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141779 CHEMBL2113529 Bioactive (2S,3S,4R,5R)-5-(6-amino-2-hexylpurin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141798 CHEMBL376968 Bioactive (2S,3S,4R,5R)-N-ethyl-5-[6-(ethylamino)-2-[(3S)-3-hydroxyoct-1-ynyl]purin-9-yl]-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141790 CHEMBL483975 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(methylamino)purin-9-yl]-3,4-dihydroxy-N-(3-methylbutyl)oxolane-2-carboxamide
CFAMM00141818 CHEMBL610655 Bioactive (2S,3S,4R)-5-(6-amino-2-hept-1-ynylpurin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141789 CHEMBL2113532 Bioactive (2S,3S,4R,5R)-5-(6-amino-2-hex-1-ynylpurin-9-yl)-N-cyclopropyl-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141795 CHEMBL205226 Bioactive (2S,3S,4R,5R)-N-ethyl-5-[6-(ethylamino)-2-[(3R)-3-hydroxybut-1-ynyl]purin-9-yl]-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141878 CHEMBL604019 Bioactive (2S,3S,4R)-5-[6-amino-2-(3-piperidin-1-ylprop-1-ynyl)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00141785 DCL000287 Clinical Trial Drug ATL-146e
CFAMM00141763 DNCL001912 Clinical Trial Drug Apadenoson
CFAMM00141850 DNC014682 Investigative Drug AdoC(Ahx)Arg6
CFAMM00141767 DNC014668 Investigative Drug AdcAhxArg6
CFAMM00141849 DNC014683 Investigative Drug AdoCGlyArg6
CFAMM00141766 DNC014669 Investigative Drug AdcAhxArg4Lys-PEGOMe
CFAMM00141848 DNC014686 Investigative Drug AdoC(betaAsp)2AlaArg6
CFAMM00141873 DNC003580 Investigative Drug NECA
CFAMM00141776 DNC014679 Investigative Drug AdoC(Aun)Arg6
CFAMM00141832 DNC014690 Investigative Drug AdoC(beta-Ala)2AlaArg6
CFAMM00141851 DNC014681 Investigative Drug AdoC(Aoc)Arg6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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