CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD2
Family Name Stromelysin-1 Inhibitor PG-530742 Family
No. of Seeds 4 No. of Other Members 23
Family Centroid CFAMM00126601 Functional Category Clinical Trial Drug with Natural Product
Superfamily Stromelysin-1 and Peroxisome proliferator-activated receptor delta Binder Superfamily
Class Class 243

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Bumetanide Family 2 11
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
D(2) dopamine receptor Ligand Rotigotine Patch Family 1 2
Neutrophil elastase Inhibitor Sivelestat Sodium Hydrate Family 2 2
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor Liga... 17 31
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 2 55
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 5-bromo... 7 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 2-[benz... 9 9
Matrix metalloproteinase-9 and Collagenase 3 inhibitor methyl ... 1 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 5-bromo... 2 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 2 9
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 6
Integrin beta-3 and Integrin alpha-IIb inhibitor (2R)-2-(benze... 4 13
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Prelamin-A/C and Cellular tumor antigen p53 inhibitor CHEMBL15... 1 2
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Neprilysin inhibitor AGN-PC-047EOU family 1 0
Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor (E)-2... 5 6
Trace amine-associated receptor 1 ligand AGN-PC-09QHOK family 1 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor 4-[4-[4... 4 4
Collagenase 3 and Stromelysin-1 inhibitor AGN-PC-0A9RJW family 1 0
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 18 2
Integrin beta-3 and Integrin alpha-IIb inhibitor [(1R)-1-(benz... 3 0
Bone morphogenetic protein 1 inhibitor 3-[[4-(benzylcarbamoyla... 1 9
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltra... 2 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 2-(4-... 3 2
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor zinc;... 4 9
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor zinc;4... 2 5
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzo... 6 7
Growth hormone secretagogue receptor type 1 ligand N-[4-[(2S)-... 1 0
Prostaglandin D2 receptor 2 ligand AGN-PC-07CQC5 family 4 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 2 1
Mineralocorticoid receptor ligand N-[3-[2-[cyclopropyl(methyl)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00126642 CHEMBL10908 Bioactive 2-[[4-[(4-bromobenzoyl)amino]phenyl]sulfonylamino]-6-phenoxyhex-4-ynoic acid
CFAMM00126607 CHEMBL10848 Bioactive SureCN7450983
CFAMM00126592 CHEMBL275700 Bioactive SureCN7454871
CFAMM00126601 DCL000002 Clinical Trial Drug PG-530742

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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