CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Multidrug resistance-associated protein 1 Inhibitor Benzbromarone Family
No. of Seeds 2 No. of Other Members 16
Family Centroid CFAMM00142723 Functional Category Clinical Trial Drug with Natural Product
Superfamily Multidrug resistance-associated protein 1 Inhibitor Benzbromarone Superfamily
Class Class 957

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand Am... 2 16
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5... 1 9
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-b... 6 21
Retinoic acid receptor RXR-alpha and Peroxisome proliferator-a... 3 17
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 2 7
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 2 7
Estrogen receptor beta and Estrogen receptor ligand AGN-PC-075... 1 0
Tyrosine-protein phosphatase non-receptor type 1 ligand (2S)-2... 9 3
5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran N... 3 0
2,4-dimethyl-5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1... 9 0


External ID

Functional Category

Molecule Name

CFAMM00142723 DCL000306 Clinical Trial Drug Benzbromarone
CFAMM00142733 DNCL001842 Clinical Trial Drug BB3

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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