CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD212
Family Name DNA topoisomerase 2-beta Inhibitor Salvicine Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00143382 Functional Category Clinical Trial Drug with Human Metabolite & Natural Product
Superfamily Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Superfamily
Class Class 368

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
Aldehyde oxidase inhibitor para-naphthoquinone Menadione Family 22 503
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
Vitamin K epoxide reductase complex subunit 1 Inhibitor Phenin... 5 44
Dihydroorotate dehydrogenase Inhibitor Polyporic Acid Family 4 13
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Cathepsin L1 Inhibitor Biphenyl-4-yl-acetaldehyde Family 2 86
Cytosolic phospholipase A2 Inhibitor 1,1,1,2,2-pentafluoro-8-p... 11 18
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,5-difluorophenyl)... 12 10
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,3,6-trifluorophen... 16 11
72 kDa type IV collagenase and Macrophage metalloelastase Inhi... 2 5
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carboxybenzyl)succ... 2 7
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 2 8
Thyroid hormone receptor beta Ligand (4-hexylphenyl)(oxiran-2-... 1 16
Liver carboxylesterase 1 Inhibitor Acenanthrene-9,10-dione Family 2 12
4-hydroxyphenylpyruvate dioxygenase Inhibitor 2-(2-iodo-benzoy... 3 1
Neuraminidase Inhibitor (e,e)-1,7-diphenyl-4,6-heptadien-3-one... 2 5
Aromatase inhibitor (6R)-6-benzyl-10,13-dimethyl-2,6,7,8,9,11,... 1 29
Retinal dehydrogenase 1 and Microtubule-associated protein tau... 1 7
Integrase inhibitor AGN-PC-00QHSA family 1 2
Sodium-dependent dopamine transporter inhibitor AGN-PC-074TA8 ... 2 5
Indanes Metabolite (R)-Pterosin B Family 5 8
Putative NP ZINC14410655 Family 6 4
(1S)-1-hydroxy-1,4-dimethyl-2,3-dihydrocyclopenta[b]anthracene... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00143382 DCL000332 Clinical Trial Drug Salvicine
CFAMM00143383 DNC013738 Investigative Drug 4-hydroxysaprothoquinone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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