CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family
No. of Seeds 10 No. of Other Members 18
Family Centroid CFAMM00143600 Functional Category Clinical Trial Drug
Superfamily P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Superfamily
Class Class 172

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
DNA Binder purine nucleoside Adenosine analog Nelarabine Family 2 10
NADH-ubiquinone oxidoreductase chain 3 Inhibitor Nadh Family 4 11
Bucladesine family 1 1
Adenosine receptor A2a Ligand Atl-146e Family 33 94
TG-C family 11 208
Histamine N-methyltransferase Inhibitor S-adenosyl-l-homocyste... 2 3
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Selenazole-... 2 1
Adenosine deaminase Inhibitor (2s,3r)-3-(6-amino-9h-purin-9-yl... 4 30
3-hydroxyacyl-CoA dehydrogenase type-2 and Mitogen-activated p... 1 1
Asparagine synthetase [glutamine-hydrolyzing] inhibitor (2R)-2... 2 1
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 16 6
2-5A-dependent ribonuclease inhibitor [[(2R,3R,4R,5R)-5-(6-ami... 13 25
Adenosine receptor A1 ligand CHEMBL2112106 family 7 7
Adenosine receptor A1 ligand CHEMBL258759 family 2 3
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 9 0
Adenosine receptor A2a and Adenosine receptor A2b ligand Cgs-2... 1 2
Adenosine receptor A2a and Adenosine receptor A2b ligand (3R,4... 7 3
Adenosine receptor A3 and Adenosine receptor A2a ligand (2R,3R... 1 1
Putative Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-di... 2 0
Carbohydrates and Carbohydrate Conjugates Metabolite 6-Thioxan... 1 0


External ID

Functional Category

Molecule Name

CFAMM00143632 CHEMBL369928 Bioactive [[[[(2R,3S,4R,5R)-5-[6-amino-2-(2,2,3,3,3-pentatritiopropylsulfanyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]-dichloromethyl]phosphonic acid
CFAMM00143622 CHEMBL2364736 Bioactive tetrasodium;[[[(2R,3S,4R,5R)-5-(6-amino-2-methylsulfanylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate
CFAMM00143631 CHEMBL336292 Bioactive AR-C67085
CFAMM00143635 CHEMBL611285 Bioactive [[(2R,3S,4R)-5-(6-amino-2-hexylsulfanylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
CFAMM00143634 CHEMBL2093075 Bioactive CHEMBL2092819
CFAMM00143600 DCL000336 Clinical Trial Drug AR-C69931 MX
CFAMM00143611 DNCL001859 Clinical Trial Drug Cangrelor

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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