CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD216
Family Name Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxaprofen Family
No. of Seeds 1 No. of Other Members 76
Family Centroid CFAMM00143709 Functional Category Clinical Trial Drug with Natural Product
Superfamily Acetyl-CoA acetyltransferase, mitochondrial Binder Superfamily
Class Class 828

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Substance-P receptor Ligand R 673 Family 2 127
FX005 family 2 1
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2... 2 27
Oestrogen receptor and Estrogen receptor beta Ligand 2-naphtha... 4 51
Oestrogen receptor and Estrogen receptor beta Ligand 2-(6-hydr... 9 22
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
5-hydroxytryptamine receptor 3A ligand 2-[(3S)-3-ethylmorpholi... 10 18
5-hydroxytryptamine receptor 3A and Potassium voltage-gated ch... 1 0
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Thyroid hormone receptor beta ligand CHEMBL1397256 family 1 12
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and Dual 3',5'... 11 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 1
Cholesteryl ester transfer protein inhibitor 2-(4-chloro-2,3-d... 1 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2,6-di... 2 4
D(4) dopamine receptor ligand SureCN8704964 family 1 2
Cellular tumor antigen p53 inhibitor CHEMBL1592002 family 1 0
Cholesteryl ester transfer protein inhibitor AGN-PC-09QKST family 1 3
Glucocorticoid receptor and Progesterone receptor ligand (8S,1... 2 0
Cholesteryl ester transfer protein inhibitor N-[4-(5-chloro-7-... 1 0
Cholesteryl ester transfer protein inhibitor AGN-PC-07R9U4 family 1 1
Arachidonate 5-lipoxygenase inhibitor (4E)-4-[(E,4Z)-4-(3H-1,3... 6 6
Bile acid receptor ligand SureCN1180444 family 1 0
(E)-2-(1,3-benzoxazol-2-yl)-3-(6-chloro-4H-1,3-benzodioxin-8-y... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00143709 DCL000338 Clinical Trial Drug Benoxaprofen

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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