CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD227
Family Name Mast/stem cell growth factor receptor Kit and Vascular endothelial growth factor receptor 2 Ligand OSI-930 Family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00144494 Functional Category Clinical Trial Drug with Natural Product
Superfamily Mast/stem cell growth factor receptor Kit and Vascular endothelial growth factor receptor 2 Ligand OSI-930 Superfamily
Class Class 973

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Multiple kinase Inhibitor MGCD265 Family 19 71
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801290 ... 3 0
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Fatty-acid amide hydrolase 1 inhibitor [3-(3-carbamoylpyrrol-1... 4 6
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Interstitial collagenase and Matrilysin inhibitor (3S,6R,7S)-N... 2 4
Vascular endothelial growth factor receptor 2 and Vascular end... 2 3
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Vascular endothelial growth factor receptor 2 and Hepatocyte g... 2 2
Vascular endothelial growth factor receptor 2 and Hepatocyte g... 1 4
Vascular endothelial growth factor receptor 2 and Vascular end... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00144494 DCL000352 Clinical Trial Drug OSI-930

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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