CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD242
Family Name Histamine H3 receptor Ligand GSK239512 Family
No. of Seeds 2 No. of Other Members 65
Family Centroid CFAMM00145542 Functional Category Clinical Trial Drug with Natural Product
Superfamily Histamine H3 receptor Ligand GSK239512 Superfamily
Class Class 963

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Neutrophil elastase inhibitor phenyl N-[(2S)-1-[(2S)-2-[[(3S)-... 2 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Neuronal acetylcholine receptor subunit beta-4 and Neuronal ac... 1 0
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Somatostatin receptor type 5 ligand AGN-PC-088VSK family 2 3
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
Sodium channel protein type 10 subunit alpha and Sodium channe... 3 22
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
Translocator protein inhibitor 2-fluoro-N-[(2-methoxyphenyl)me... 8 27
Histamine H3 receptor ligand 3-[4-[3-[(2R)-2-methylpyrrolidin-... 1 5
Mu-type opioid receptor ligand AGN-PC-075GBK family 4 4
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 2
Growth hormone secretagogue receptor type 1 and Potassium volt... 2 0
Beta-1 adrenergic receptor ligand N-[2-[[(2S)-3-(2-cyanophenox... 2 1
Histamine H3 receptor ligand 6-[[2-[2-[(2R)-2-methylpyrrolidin... 2 0
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 2 1
Motilin receptor ligand SureCN2768193 family 2 1
Motilin receptor ligand SureCN2765637 family 1 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Glutamate receptor ionotropic, NMDA 2B ligand SureCN5532501 fa... 1 0
72 kDa type IV collagenase and Aminopeptidase N inhibitor ly52... 1 0
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 6 1
C-C chemokine receptor type 8 and Potassium voltage-gated chan... 5 1
Reverse transcriptase/RNaseH inhibitor 3Am-6Et-7,9-diMe-PBOA-5... 4 1
Platelet-activating factor receptor ligand AGN-PC-001U4L family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00145542 DCL000374 Clinical Trial Drug GSK239512
CFAMM00145532 DNC002343 Investigative Drug GSK189254A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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