CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD249
Family Name Orexin receptor type 1 Ligand SB-649868 Family
No. of Seeds 7 No. of Other Members 3
Family Centroid CFAMM00145913 Functional Category Clinical Trial Drug
Superfamily Orexin receptor type 1 Ligand SB-649868 Superfamily
Class Class 985

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 inhibitor 2-(4-phenoxyphe... 1 10
Metabotropic glutamate receptor 5 ligand (3-methoxyphenyl)-[2-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00145906 CHEMBL2031481 Bioactive AGN-PC-04XOK7
CFAMM00145905 CHEMBL2031480 Bioactive N-[[1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
CFAMM00145912 CHEMBL2031501 Bioactive N-[[(2S)-5-fluoro-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
CFAMM00145911 CHEMBL2031504 Bioactive N-[[(2S,6S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-6-methylpiperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
CFAMM00145903 CHEMBL2031485 Bioactive N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
CFAMM00145908 CHEMBL2031490 Bioactive N-[[(2S,3R)-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)-3-(trifluoromethyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
CFAMM00145913 DCL000386 Clinical Trial Drug SB-649868

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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