CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD25
Family Name C-X-C chemokine receptor type 4 Ligand AMD-3100 Family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00129360 Functional Category Clinical Trial Drug
Superfamily C-X-C chemokine receptor type 4 Ligand AMD-3100 Superfamily
Class Class 832

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Bethanidine Family 2 22
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Adrenergic neuron Inhibitor guanidine isoquinoline analog Debr... 2 44
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Renin Inhibitor N-methyl-n-(methylbenzyl)formamide Family 2 17
Sphingosine 1-phosphate receptor 1 Ligand [3-(4-nonyl-benzylam... 9 22
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 6
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 6
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor Sodium... 1 10
Sodium-dependent serotonin transporter and Sodium-dependent no... 9 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 5
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 2
Histamine H3 receptor ligand 1-[4-[4-(pyrrolidin-1-ylmethyl)ph... 4 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor (1... 3 0
1-[(E)-3-phenylprop-2-enyl]-4-[[(4S)-4-prop-1-en-2-ylcyclohexe... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00129365 CHEMBL2311089 Bioactive Plerixafor hydrochloride
CFAMM00129364 DCL000922 Clinical Trial Drug Plerixafor
CFAMM00129360 DCL000041 Clinical Trial Drug AMD-3100

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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