CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Sodium channel Ligand GSK1014802 Family
No. of Seeds 4 No. of Other Members 92
Family Centroid CFAMM00146727 Functional Category Clinical Trial Drug
Superfamily Sodium channel Ligand GSK1014802 Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Carprofen Family 1 5
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Glutamate receptor ionotropic, NMDA 1 ligand (3S)-3-[2-[4-(ami... 2 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 3 6
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Prelamin-A/C and Bloom syndrome protein inhibitor 7-Chlorokynu... 1 10
Vasopressin V2 receptor ligand AGN-PC-072QIH family 1 3
D-amino-acid oxidase inhibitor SureCN679780 family 1 5
C-C chemokine receptor type 2 ligand AGN-PC-03NT5I family 5 18
Glutamate receptor ionotropic, NMDA 1 ligand AGN-PC-0ABXNN family 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 0


External ID

Functional Category

Molecule Name

CFAMM00146727 DCL000400 Clinical Trial Drug GSK1014802
CFAMM00146699 DNC011990 Investigative Drug 3-Carbamoyl-6-chloro-1H-indole-2-carboxylic acid
CFAMM00146632 DNC003483 Investigative Drug Mdl-29951
CFAMM00146728 DNC012841 Investigative Drug MDL-105519

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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