CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD262
Family Name Bcl-2-like protein 1 and Apoptosis regulator Bcl-2 Inhibitor ABT-263 Family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00146945 Functional Category Clinical Trial Drug
Superfamily Bcl-2-like protein 1 and Apoptosis regulator Bcl-2 Inhibitor ABT-263 Superfamily
Class Class 993

Cousin Family NamesSeedsMembers
Apoptosis regulator Bcl-2 Inhibitor ABT-737 Family 62 50
Bcl-2-like protein 1 and Apoptosis regulator Bcl-2 inhibitor S... 2 0
Bcl-2-like protein 1 and Apoptosis regulator Bcl-2 inhibitor S... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00146941 CHEMBL508865 Bioactive 4-[4-[[2-(4-chlorophenyl)cyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
CFAMM00146946 CHEMBL501889 Bioactive 4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
CFAMM00146939 CHEMBL508210 Bioactive SureCN2018636
CFAMM00146945 DCL000415 Clinical Trial Drug ABT-263

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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