CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD264
Family Name Peroxisome proliferator-activated receptor alpha Ligand Aleglitazar Family
No. of Seeds 29 No. of Other Members 7
Family Centroid CFAMM00147200 Functional Category Clinical Trial Drug
Superfamily Peroxisome proliferator-activated receptor alpha Ligand Aleglitazar Superfamily
Class Class 994

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Peroxisome proliferator-activated receptor alpha and Peroxisom... 5 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Peroxisome proliferator-activated receptor gamma and Peroxisom... 5 0
Peroxisome proliferator-activated receptor alpha ligand 5-[4-[... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 3
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 5 5
Peroxisome proliferator-activated receptor gamma and Tyrosine-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00147207 CHEMBL484001 Bioactive (2S)-2-(cyclopropylmethoxy)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl]propanoic acid
CFAMM00147191 CHEMBL1813003 Bioactive (2S)-2-ethoxy-3-[4-[(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)methoxy]phenyl]propanoic acid
CFAMM00147206 CHEMBL482740 Bioactive AGN-PC-01NRBV
CFAMM00147190 CHEMBL484409 Bioactive SureCN5759618
CFAMM00147205 CHEMBL483341 Bioactive AGN-PC-01NRF9
CFAMM00147189 CHEMBL484607 Bioactive (2S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl]-2-(2,2,2-trifluoroethoxy)propanoic acid
CFAMM00147198 CHEMBL1813006 Bioactive (2S)-2-ethoxy-3-[4-[[5-methyl-2-(5-methylthiophen-2-yl)-1,3-oxazol-4-yl]methoxy]phenyl]propanoic acid
CFAMM00147204 CHEMBL1813008 Bioactive (2S)-2-ethoxy-3-[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]phenyl]propanoic acid
CFAMM00147197 CHEMBL82602 Bioactive SureCN5116770
CFAMM00147210 CHEMBL1813004 Bioactive (2S)-2-ethoxy-3-[4-[(5-methyl-2-thiophen-3-yl-1,3-oxazol-4-yl)methoxy]phenyl]propanoic acid
CFAMM00147188 CHEMBL519351 Bioactive (2S)-2-ethoxy-3-[7-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-4-yl]propanoic acid
CFAMM00147194 CHEMBL484137 Bioactive SureCN5762425
CFAMM00147203 CHEMBL1813009 Bioactive (2S)-2-ethoxy-3-[4-[2-(5-methyl-2-thiophen-3-yl-1,3-oxazol-4-yl)ethoxy]phenyl]propanoic acid
CFAMM00147209 CHEMBL1813005 Bioactive (2S)-2-ethoxy-3-[4-[[5-methyl-2-(3-methylthiophen-2-yl)-1,3-oxazol-4-yl]methoxy]phenyl]propanoic acid
CFAMM00147193 CHEMBL1813010 Bioactive (2S)-2-ethoxy-3-[4-[2-[5-methyl-2-(3-methylthiophen-2-yl)-1,3-oxazol-4-yl]ethoxy]phenyl]propanoic acid
CFAMM00147202 CHEMBL521007 Bioactive SureCN5760201
CFAMM00147208 CHEMBL484000 Bioactive SureCN5760448
CFAMM00147201 CHEMBL77502 Bioactive LY-510929
CFAMM00147192 CHEMBL485188 Bioactive (2S)-2-(cyclopropylmethoxy)-3-[4-[2-[5-methyl-2-(4-propan-2-ylphenyl)-1,3-oxazol-4-yl]ethoxy]-1-benzothiophen-7-yl]propanoic acid
CFAMM00147214 CHEMBL1813011 Bioactive (2S)-2-ethoxy-3-[4-[2-[5-methyl-2-(5-methylthiophen-2-yl)-1,3-oxazol-4-yl]ethoxy]phenyl]propanoic acid
CFAMM00147200 DCL000419 Clinical Trial Drug Aleglitazar

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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