CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin D2 receptor 2 Ligand AZD1981 Family
No. of Seeds 11 No. of Other Members 28
Family Centroid CFAMM00148005 Functional Category Clinical Trial Drug
Superfamily Prostaglandin D2 receptor 2 Ligand AZD1981 Superfamily
Class Class 1005

Cousin Family NamesSeedsMembers
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
Prostaglandin E synthase Inhibitor L-655240 Family 3 46
Aldose reductase Inhibitor Lidorestat Family 16 27
Prostaglandin D2 receptor 2 Ligand L-888607 Family 2 22
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 4 19
Prostaglandin D2 receptor 2 and Aldose reductase ligand 2-[5-c... 1 0
Prostaglandin D2 receptor 2 ligand 2-[3-(4-chlorophenyl)sulfan... 2 1
Prostaglandin D2 receptor 2 ligand 2-[5-fluoro-2-methyl-3-[(4-... 3 5
Prostaglandin D2 receptor and Thromboxane A2 receptor ligand A... 12 0
Prostaglandin D2 receptor 2 ligand SureCN2516080 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00148030 CHEMBL1917426 Bioactive 2-[3-(4-chlorophenyl)sulfanyl-5-fluoro-2-methylindol-1-yl]acetic acid
CFAMM00148036 CHEMBL1917449 Bioactive 2-[4-acetamido-3-(4-chlorophenyl)sulfonyl-2-methylindol-1-yl]acetic acid
CFAMM00148015 CHEMBL1917433 Bioactive 2-[3-(4-chlorophenyl)sulfanyl-4-(methanesulfonamido)-2-methylindol-1-yl]acetic acid
CFAMM00148029 CHEMBL1917447 Bioactive 2-[3-(4-chlorophenyl)sulfonyl-5-fluoro-2-methylindol-1-yl]acetic acid
CFAMM00148013 CHEMBL1917450 Bioactive 2-[3-(4-chlorophenyl)sulfonyl-4-(methanesulfonamido)-2-methylindol-1-yl]acetic acid
CFAMM00148019 CHEMBL1917441 Bioactive 2-[3-(3-chlorophenyl)sulfanyl-2,5-dimethylindol-1-yl]acetic acid
CFAMM00148032 CHEMBL1917442 Bioactive 2-[3-(2-chlorophenyl)sulfanyl-2,5-dimethylindol-1-yl]acetic acid
CFAMM00148011 CHEMBL1917438 Bioactive 2-[3-(4-chlorophenyl)sulfanyl-2-methyl-4-phenylindol-1-yl]acetic acid
CFAMM00148031 CHEMBL1917427 Bioactive 2-[3-(4-chlorophenyl)sulfanyl-5-fluoro-2,4-dimethylindol-1-yl]acetic acid
CFAMM00148010 CHEMBL1917439 Bioactive 2-[3-(4-chlorophenyl)sulfanyl-2-methyl-5-phenylindol-1-yl]acetic acid
CFAMM00148005 DCL000460 Clinical Trial Drug AZD1981

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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