CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD289
Family Name Serine/threonine-protein kinase mTOR Inhibitor AZD8055 Family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00148432 Functional Category Clinical Trial Drug
Superfamily Serine/threonine-protein kinase mTOR Inhibitor AZD8055 Superfamily
Class Class 976

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 19 11
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Adenosine receptor A1 and Adenosine receptor A2a ligand (6E)-6... 2 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 17
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Tyrosine-protein kinase Lck inhibitor 3-[[2-(benzimidazol-1-yl... 2 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 1
Adenosine receptor A1 and Adenosine receptor A2a ligand 7-meth... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00148430 CHEMBL1078983 Bioactive Ku-0063794
CFAMM00148432 DCL000481 Clinical Trial Drug AZD8055

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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