CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD294
Family Name Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Family
No. of Seeds 3 No. of Other Members 16
Family Centroid CFAMM00148598 Functional Category Clinical Trial Drug with Human Metabolite
Superfamily Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Superfamily
Class Class 445

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
4-hydroxyphenylpyruvate dioxygenase Inhibitor Nitisinone Family 4 43
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Pan-DAC Inhibitor AR-42 Family 21 153
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Urokinase-type plasminogen activator Inhibitor 1-[4-(2-oxo-2-p... 1 3
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
Liver carboxylesterase 1 Inhibitor 1-(4-nitro-phenyl)-2-phenyl... 2 7
Transient receptor potential cation channel subfamily V member... 6 33
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 13
Amyloid beta A4 protein Inhibitor 1,6-bis(4'-nitrophenyl)-hexa... 3 60
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 1 9
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Telomerase reverse transcriptase Inhibitor 2,7-dinitroantraqui... 3 8
Acetylcholinesterase and Cholinesterase Inhibitor 5,6-dinitroa... 1 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(4-... 1 9
Transient receptor potential cation channel subfamily V member... 1 5
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 9 7
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
Myeloperoxidase Inhibitor 4-aminobenzoic Acid Hydrazide Family 1 3
Progesterone receptor and Androgen receptor ligand AGN-PC-080P... 4 27
Acetylcholinesterase inhibitor tmtfa family 1 2
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor AGN-P... 2 0
Aromatase inhibitor AGN-PC-00Q2PJ family 4 0
P2X purinoceptor 7 inhibitor 2-cyclohexyl-N'-(2-methylphenyl)a... 3 11
Prostaglandin G/H synthase 2 inhibitor (2Z)-1-(4-chlorophenyl)... 1 1
D-alanyl-D-alanine carboxypeptidase and Penicillin-binding pro... 1 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
2-(4-aminophenyl)butanedioate NP ZINC31165273 Family 4 12
3-prop-2-enyl-1H-quinolin-4-one NP 6-amino-2-methylquinolin-4-... 5 3
NP 1-(3-isothiocyanatophenyl)ethanone Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00148598 DCL000500 Clinical Trial Drug BSI-201
CFAMM00148579 DNC000058 Investigative Drug 3-aminobenzamide
CFAMM00148581 DNC005265 Investigative Drug WR-089120

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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