CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00148612 Functional Category Clinical Trial Drug
Superfamily Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Superfamily
Class Class 1002

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Apricoxib family 8 77
Indeglitazar family 3 39
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 1 0
5-hydroxytryptamine receptor 6 ligand N-[3-[[(2R)-1-methylpyrr... 6 0
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 1 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-hydro... 3 25
Disintegrin and metalloproteinase domain-containing protein 17... 1 3
Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N... 4 1
Collagenase 3 and A disintegrin and metalloproteinase with thr... 5 6
5-hydroxytryptamine receptor 6 ligand SureCN5253197 family 4 2
Collagenase 3 and Neutrophil collagenase inhibitor 2-[1-(2-met... 2 0
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 2 0
Oxytocin receptor and Vasopressin V1a receptor ligand 4-methox... 9 8
Menin and Histone-lysine N-methyltransferase 2A inhibitor 3-{4... 1 0
Thromboxane-A synthase inhibitor AGN-PC-00FAD1 family 2 2
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 4 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 4
Pol polyprotein inhibitor AC1LASR0 family 2 1


External ID

Functional Category

Molecule Name

CFAMM00148604 CHEMBL338241 Bioactive (E)-6-[4-[2-[(4-methoxyphenyl)sulfonylamino]ethyl]phenyl]-6-pyridin-3-ylhex-5-enoic acid
CFAMM00148612 DCL000505 Clinical Trial Drug CP-533536

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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