CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Cholesteryl ester transfer protein Inhibitor CP-800569 Family
No. of Seeds 5 No. of Other Members 81
Family Centroid CFAMM00148655 Functional Category Clinical Trial Drug
Superfamily Cholesteryl ester transfer protein Inhibitor CP-800569 Superfamily
Class Class 1015

Cousin Family NamesSeedsMembers
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Cholesteryl ester transfer protein Inhibitor Tetrahydroquinoli... 3 8
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00G... 16 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 2


External ID

Functional Category

Molecule Name

CFAMM00148640 CHEMBL446661 Bioactive (2R)-3-[3-(3-ethylphenoxy)-N-[[3-(1,1,2,2-tetrafluoroethoxy)phenyl]methyl]anilino]-1,1,1-trifluoropropan-2-ol
CFAMM00148643 CHEMBL67117 Bioactive (2R)-1,1,1-trifluoro-3-[3-(4-methylphenoxy)-N-[[3-(1,1,2,2-tetrafluoroethoxy)phenyl]methyl]anilino]propan-2-ol
CFAMM00148656 CHEMBL69563 Bioactive 3-[3-(4-chloro-3-ethylphenoxy)-N-[[3-(1,1,2,2-tetrafluoroethoxy)phenyl]methyl]anilino]-1,1,1-trifluoropropan-2-ol
CFAMM00148655 DCL000507 Clinical Trial Drug CP-800569
CFAMM00148691 DNC003669 Investigative Drug SC-795

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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