CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD303
Family Name Glucagon receptor Ligand Dwlip-gcgrrx Family
No. of Seeds 5 No. of Other Members 26
Family Centroid CFAMM00149344 Functional Category Clinical Trial Drug
Superfamily Glucagon receptor Ligand Dwlip-gcgrrx Superfamily
Class Class 1022

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Histamine H1 receptor Ligand Triprolidine Family 19 316
Neuromedin-K receptor Ligand SB222200 Family 17 235
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 55
Lethal factor Inhibitor N,n'-bis(4-amino-2-methylquinolin-6-yl... 2 11
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 43 17
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Urotensin-2 receptor Ligand Palosuran Family 4 4
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 1 1
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 1 3
Metabotropic glutamate receptor 5 Ligand 7-m-tolyl-1,6-naphthy... 4 2
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 0
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Protein kinase C theta type and Protein kinase C delta type in... 16 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YYL... 1 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 5 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 3 3
Hepatocyte growth factor receptor ligand AGN-PC-08XYH0 family 8 4
Hepatocyte growth factor receptor ligand AGN-PC-08XYH3 family 1 0
Hepatocyte growth factor receptor ligand AGN-PC-09M1N4 family 2 0
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
Melanin-concentrating hormone receptor 1 ligand SureCN6198980 ... 13 0
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 2
CGMP-dependent protein kinase inhibitor methyl 2-[[4-[5-(4-flu... 6 1
Cholinesterase and Acetylcholinesterase inhibitor [2,2-dimethy... 2 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 5
CGMP-dependent protein kinase inhibitor AGN-PC-078XQ0 family 1 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00149352 CHEMBL270491 Bioactive 3-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propylamino]propyl nitrate
CFAMM00149338 CHEMBL272229 Bioactive 2-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propylamino]ethyl nitrate
CFAMM00149337 CHEMBL407320 Bioactive AGN-PC-04RKYO
CFAMM00149344 DCL000520 Clinical Trial Drug DwLIP-GCGRrx
CFAMM00149347 DNC001023 Investigative Drug Nitracrine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543