CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD31
Family Name Cholesteryl ester transfer protein Inhibitor Anacetrapib Family
No. of Seeds 3 No. of Other Members 63
Family Centroid CFAMM00129466 Functional Category Clinical Trial Drug
Superfamily Cholesteryl ester transfer protein Inhibitor Anacetrapib Superfamily
Class Class 837

Cousin Family NamesSeedsMembers
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Kappa-type opioid receptor Ligand ICI-204448 Family 7 26
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 12 0
Prostaglandin D2 receptor 2 ligand SureCN137334 family 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Prostaglandin E2 receptor EP4 subtype ligand 4-[(1S)-1-[[2-(tr... 2 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Kappa-type opioid receptor ligand N-[(1S)-2-[(3S)-3-hydroxypyr... 2 0
Cholesteryl ester transfer protein inhibitor (4S,5R)-5-[3,5-bi... 1 1
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00129525 CHEMBL1916710 Bioactive 2-[3-[2-[[ethyl-[(4-fluorophenyl)methoxycarbonyl]amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid
CFAMM00129524 CHEMBL1916711 Bioactive 2-[3-[2-[[(3,5-difluorophenyl)methoxycarbonyl-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid
CFAMM00129466 DCL000048 Clinical Trial Drug Anacetrapib

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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