CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor MK-0524B Family
No. of Seeds 3 No. of Other Members 32
Family Centroid CFAMM00150472 Functional Category Clinical Trial Drug
Superfamily 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor MK-0524B Superfamily
Class Class 1029

Cousin Family NamesSeedsMembers
Prostaglandin E synthase Inhibitor L-655240 Family 3 46
Prostaglandin D2 receptor 2 Ligand L-888607 Family 2 22
Prostaglandin D2 receptor and Thromboxane A2 receptor ligand S... 3 4
Prostaglandin D2 receptor and Thromboxane A2 receptor ligand A... 5 3
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0


External ID

Functional Category

Molecule Name

CFAMM00150472 DCL000565 Clinical Trial Drug MK-0524B
CFAMM00150485 DNC007126 Investigative Drug DIASTEREOMER 2
CFAMM00150505 DPR000067 Investigative Drug Laropiprant+niacin

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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