CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD315
Family Name Gamma secretase Inhibitor MK-0752 Family
No. of Seeds 4 No. of Other Members 15
Family Centroid CFAMM00150510 Functional Category Clinical Trial Drug
Superfamily Gamma secretase Inhibitor MK-0752 Superfamily
Class Class 1030

Cousin Family NamesSeedsMembers
Presenilin-1 and Presenilin-2 Inhibitor 1-chloro-4-(1-phenyl-c... 5 13
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 1 4
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-050UV0 family 3 0
Presenilin-1 and Presenilin-2 inhibitor 3-[(1S,3S)-3-(4-chloro... 2 0
Presenilin-1 and Presenilin-2 inhibitor methyl (E)-4-[(1S,3S)-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00150519 CHEMBL377206 Bioactive methyl 4-[(1R,3S)-3-(4-chlorophenyl)sulfonyl-3-(2,5-difluorophenyl)cyclohexyl]butanoate
CFAMM00150511 CHEMBL383826 Bioactive AGN-PC-045QAN
CFAMM00150527 CHEMBL377413 Bioactive methyl 4-[(1R,3S)-3-(4-chlorophenyl)sulfonyl-3-(2,5-difluorophenyl)-1-methylcyclohexyl]butanoate
CFAMM00150510 DCL000567 Clinical Trial Drug MK-0752

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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