CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD32
Family Name B2 bradykinin receptor Ligand Anatibant Family
No. of Seeds 49 No. of Other Members 15
Family Centroid CFAMM00129563 Functional Category Clinical Trial Drug
Superfamily B2 bradykinin receptor Ligand Anatibant Superfamily
Class Class 838

Cousin Family NamesSeedsMembers
B2 bradykinin receptor Ligand FR-173657 Family 44 180
B2 bradykinin receptor ligand SureCN6578325 family 2 1
B2 bradykinin receptor ligand 2-(4-aminobutylcarbamoylamino)-N... 5 0
B2 bradykinin receptor ligand SureCN7749611 family 4 1
B2 bradykinin receptor ligand 4-[(E)-3-[[2-[2,4-dichloro-3-[[4... 29 2
B2 bradykinin receptor ligand SureCN6640854 family 7 4
B2 bradykinin receptor ligand AGN-PC-073GJI family 2 4
B2 bradykinin receptor ligand [(4S)-4-amino-5-[4-[4-[[2,4-dich... 1 0
B2 bradykinin receptor ligand 4-[(E)-3-[[1-[2,4-dichloro-3-[(4... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00129550 CHEMBL209719 Bioactive 2-[6-[4-[2-[[2,4-dichloro-3-[(2-methylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]-2-methylpropanoyl]piperazin-1-yl]hexyl]guanidine
CFAMM00129576 CHEMBL376866 Bioactive [(3S)-3-amino-4-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-4-oxobutyl]-trimethylazanium
CFAMM00129589 CHEMBL220591 Bioactive 2,4-dichloro-N-[1-[4-[(2S)-2,6-diaminohexanoyl]piperazine-1-carbonyl]cyclopentyl]-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129556 CHEMBL221285 Bioactive [(2S)-6-(diaminomethylideneamino)-1-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-1-oxohexan-2-yl]-trimethylazanium
CFAMM00129534 CHEMBL1956855 Bioactive 2,4-dichloro-N-[4-[4-[(2S)-2,5-diaminopentanoyl]piperazine-1-carbonyl]oxan-4-yl]-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide;2,2,2-trifluoroacetic acid
CFAMM00129569 CHEMBL375576 Bioactive 2,4-dichloro-N-[1-[4-[(3S)-3,6-diaminohexanoyl]piperazine-1-carbonyl]cyclopentyl]-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129582 CHEMBL218636 Bioactive [(4S)-5-[4-[1-acetyl-4-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]piperidine-4-carbonyl]piperazin-1-yl]-4-amino-5-oxopentyl]-trimethylazanium
CFAMM00129549 CHEMBL267493 Bioactive 2-[(4S)-4-amino-6-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-6-oxohexyl]guanidine
CFAMM00129562 CHEMBL375820 Bioactive 2-[(5S)-5-amino-6-[4-[2-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]-2-methylpropanoyl]piperazin-1-yl]-6-oxohexyl]guanidine
CFAMM00129588 CHEMBL383167 Bioactive N-[1-[4-[(2S)-2-amino-6-(dimethylamino)hexanoyl]piperazin-1-yl]-2-methyl-1-oxopropan-2-yl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129533 CHEMBL1956854 Bioactive N-[4-[4-(5-aminopentanoyl)piperazine-1-carbonyl]oxan-4-yl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide;2,2,2-trifluoroacetic acid
CFAMM00129542 CHEMBL1956858 Bioactive N-[4-[4-[(2S)-2-amino-6-(dimethylamino)hexanoyl]piperazine-1-carbonyl]oxan-4-yl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide;2,2,2-trifluoroacetic acid
CFAMM00129555 CHEMBL380273 Bioactive N-[1-[4-[(2S)-2-amino-5-(dimethylamino)pentanoyl]piperazin-1-yl]-2-methyl-1-oxopropan-2-yl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129568 CHEMBL210788 Bioactive N-[1-[4-[(3S)-3-amino-7-(dimethylamino)heptanoyl]piperazin-1-yl]-2-methyl-1-oxopropan-2-yl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129548 CHEMBL218540 Bioactive [(2S)-1-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-1-oxo-5-(trimethylazaniumyl)pentan-2-yl]-trimethylazanium
CFAMM00129574 CHEMBL206312 Bioactive N'-(6-aminohexyl)-4-[2-[[2,4-dichloro-3-[(2-methylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]-2-methylpropanoyl]piperazine-1-carboximidamide
CFAMM00129532 CHEMBL374224 Bioactive [(2S)-1-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-1-oxo-6-(trimethylazaniumyl)hexan-2-yl]-trimethylazanium
CFAMM00129541 CHEMBL378237 Bioactive N'-(3-aminopropyl)-4-[2-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]-2-methylpropanoyl]piperazine-1-carboximidamide
CFAMM00129554 CHEMBL222156 Bioactive 2-[6-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-6-oxohexyl]guanidine
CFAMM00129567 CHEMBL205093 Bioactive N-[1-[4-[(3S)-3-amino-6-(dimethylamino)hexanoyl]piperazin-1-yl]-2-methyl-1-oxopropan-2-yl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129580 CHEMBL415151 Bioactive [(4S)-4-amino-6-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-6-oxohexyl]-trimethylazanium
CFAMM00129538 CHEMBL1956853 Bioactive 2,4-dichloro-N-[4-[4-[5-(dimethylamino)pentanoyl]piperazine-1-carbonyl]oxan-4-yl]-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide;2,2,2-trifluoroacetic acid
CFAMM00129593 CHEMBL373607 Bioactive [(4S)-4-amino-5-[4-[4-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]-1-methylpiperidine-4-carbonyl]piperazin-1-yl]-5-oxopentyl]-trimethylazanium
CFAMM00129586 CHEMBL220693 Bioactive [(4S)-4-amino-5-[4-[4-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]piperidine-4-carbonyl]piperazin-1-yl]-5-oxopentyl]-trimethylazanium
CFAMM00129531 CHEMBL386794 Bioactive [5-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-5-oxopentyl]-trimethylazanium
CFAMM00129566 CHEMBL375354 Bioactive [(2S)-6-amino-1-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-1-oxohexan-2-yl]-trimethylazanium
CFAMM00129579 CHEMBL221683 Bioactive [4-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-4-oxobutyl]-trimethylazanium
CFAMM00129592 CHEMBL220595 Bioactive N-[1-[4-[(2S)-2-amino-6-(dimethylamino)hexanoyl]piperazine-1-carbonyl]cyclopentyl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129537 CHEMBL220478 Bioactive [(3S)-6-amino-1-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-1-oxohexan-3-yl]-trimethylazanium
CFAMM00129546 CHEMBL218427 Bioactive [(4S)-4-amino-5-[4-[4-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]oxane-4-carbonyl]piperazin-1-yl]-5-oxopentyl]-trimethylazanium
CFAMM00129559 CHEMBL539924 Bioactive 4-carbamimidoyl-N-[4-[(2S)-1-[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylpyrrolidin-2-yl]-4-oxobutyl]benzamide
CFAMM00129539 CHEMBL541758 Bioactive SureCN3552797
CFAMM00129552 CHEMBL415152 Bioactive [2-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-2-oxoethyl]-trimethylazanium
CFAMM00129565 CHEMBL207939 Bioactive (2R)-N-[3-[(4-carbamimidoylbenzoyl)amino]propyl]-1-[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylpyrrolidine-2-carboxamide
CFAMM00129530 CHEMBL266493 Bioactive 3-[[amino-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]methylidene]amino]propyl-trimethylazanium
CFAMM00129578 CHEMBL1956718 Bioactive 2-[(4S)-4-amino-5-[4-[4-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]oxane-4-carbonyl]piperazin-1-yl]-5-oxopentyl]guanidine;2,2,2-trifluoroacetic acid
CFAMM00129591 CHEMBL220596 Bioactive N-[1-[4-[(3S)-3-amino-6-(dimethylamino)hexanoyl]piperazine-1-carbonyl]cyclopentyl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129536 CHEMBL1956857 Bioactive 2,4-dichloro-N-[4-[4-[(2S)-2,6-diaminohexanoyl]piperazine-1-carbonyl]oxan-4-yl]-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide;2,2,2-trifluoroacetic acid
CFAMM00129545 CHEMBL374272 Bioactive N-[1-[4-[(2S)-2,6-bis(dimethylamino)hexanoyl]piperazine-1-carbonyl]cyclopentyl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide
CFAMM00129558 CHEMBL249235 Bioactive 4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]-N'-[3-(dimethylamino)propyl]piperazine-1-carboximidamide
CFAMM00129571 CHEMBL387452 Bioactive [(4S)-4-amino-5-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-5-oxopentyl]-trimethylazanium
CFAMM00129551 CHEMBL206474 Bioactive 2-[(5S)-5-amino-7-[4-[2-[[2,4-dichloro-3-[(2-methylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]-2-methylpropanoyl]piperazin-1-yl]-7-oxoheptyl]guanidine
CFAMM00129577 CHEMBL1956719 Bioactive 2-[(5S)-5-amino-6-[4-[4-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]oxane-4-carbonyl]piperazin-1-yl]-6-oxohexyl]guanidine;2,2,2-trifluoroacetic acid
CFAMM00129590 CHEMBL222167 Bioactive [6-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-6-oxohexyl]-trimethylazanium
CFAMM00129544 CHEMBL375689 Bioactive 2-[(5S)-5-amino-6-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-6-oxohexyl]guanidine
CFAMM00129535 CHEMBL1956856 Bioactive N-[4-[4-[(2S)-2-amino-5-(dimethylamino)pentanoyl]piperazine-1-carbonyl]oxan-4-yl]-2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide;2,2,2-trifluoroacetic acid
CFAMM00129570 CHEMBL374273 Bioactive [(5S)-5-amino-6-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-6-oxohexyl]-trimethylazanium
CFAMM00129583 CHEMBL373459 Bioactive [(2S)-5-amino-1-[4-[1-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-1-oxopentan-2-yl]-trimethylazanium
CFAMM00129563 DCL000050 Clinical Trial Drug Anatibant

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543