CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Adenosine receptor A1 Ligand MK-7418 Family
No. of Seeds 21 No. of Other Members 116
Family Centroid CFAMM00150620 Functional Category Clinical Trial Drug with Natural Product
Superfamily Adenosine receptor A1 Ligand MK-7418 Superfamily
Class Class 940

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor xant... 18 210
Tumor necrosis factor inhibitor xanthine derivative Pentoxifyl... 5 69
xanthine alkaloid Theobromine family 6 10
Adenosine receptor A1 Ligand CVT-124 Family 5 6
Adenosine receptor A2a Ligand BG-9928 Family 8 11
UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor RW... 1 0
Adenosine receptor A1 and Adenosine receptor A2a ligand CHEMBL... 2 0
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand NSC14... 1 2
Adenosine receptor A1 and Adenosine receptor A2b ligand 8-cycl... 1 4
Adenosine receptor A1 and Adenosine receptor A2b ligand 8-(1-$... 2 2
Dipeptidyl peptidase 4 inhibitor SureCN554974 family 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 1 0


External ID

Functional Category

Molecule Name

CFAMM00150664 CHEMBL134837 Bioactive N-[[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)cyclohexyl]methyl]acetamide
CFAMM00150621 CHEMBL284578 Bioactive 1H-Purine-2,6-dione, 8-cyclopentyl-3,7-dihydro-3-methyl-1-propyl-
CFAMM00150651 CHEMBL318607 Bioactive 1,3-dibutyl-8-cyclopentyl-7H-purine-2,6-dione
CFAMM00150602 CHEMBL320872 Bioactive SureCN7270718
CFAMM00150729 CHEMBL418101 Bioactive SureCN7269366
CFAMM00150721 CHEMBL160369 Bioactive 106686-66-2
CFAMM00150661 CHEMBL321505 Bioactive 8-cyclohexyl-1,3-dimethyl-3,9-dihydro-1h-purine-2,6-dione
CFAMM00150613 CHEMBL1628611 Bioactive [3H]DPCPX
CFAMM00150720 CHEMBL77717 Bioactive CHEMBL77717
CFAMM00150727 CHEMBL285074 Bioactive 8-cyclohexyl-3-methyl-1-propyl-7H-purine-2,6-dione
CFAMM00150604 CHEMBL104491 Bioactive SureCN7269103
CFAMM00150724 CHEMBL416585 Bioactive 8-cyclohexyl-1-methyl-3-propyl-7H-purine-2,6-dione
CFAMM00150620 DCL000573 Clinical Trial Drug MK-7418
CFAMM00150649 DNC006933 Investigative Drug 3-noradamantyl-1,3-dipropylxanthine
CFAMM00150618 DNC001096 Investigative Drug PD-116,948

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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