CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD33
Family Name Glucose-dependent insulinotropic receptor Ligand APD668 Family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00129609 Functional Category Clinical Trial Drug
Superfamily Glucose-dependent insulinotropic receptor Ligand APD668 Superfamily
Class Class 839

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
Poly [ADP-ribose] polymerase 1 inhibitor 8-[[4-fluoro-3-(4-pyr... 5 2
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... 5 0
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Cathepsin S and Cathepsin K inhibitor AGN-PC-00CD7W family 5 5
Poly [ADP-ribose] polymerase 1 inhibitor Piperazine analogue, ... 4 0
Melanin-concentrating hormone receptor 1 and Alpha-2A adrenerg... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00129597 CHEMBL49630 Bioactive 1,1-dioxo-2-[[(1S,2S)-2-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]cyclopropyl]methyl]-1,2-benzothiazol-3-one
CFAMM00129594 CHEMBL543248 Bioactive AGN-PC-07BY6Q
CFAMM00129609 DCL000051 Clinical Trial Drug APD668

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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