CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name D(3) dopamine receptor Ligand PF-217830 Family
No. of Seeds 21 No. of Other Members 7
Family Centroid CFAMM00152328 Functional Category Clinical Trial Drug
Superfamily D(3) dopamine receptor Ligand PF-217830 Superfamily
Class Class 974

Cousin Family NamesSeedsMembers
Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Fa... 3 95
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 3 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Renin and Cytochrome P450 3A4 inhibitor AGN-PC-046RG9 family 8 28
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 4 9
C-X-C chemokine receptor type 3 ligand 1-[3-[[(1R,5S)-3-[(5-fl... 3 2
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 5
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Acyl-CoA desaturase inhibitor SureCN1182546 family 2 5


External ID

Functional Category

Molecule Name

CFAMM00152332 CHEMBL1774069 Bioactive AGN-PC-035FFA
CFAMM00152319 CHEMBL1774072 Bioactive AGN-PC-035FHC
CFAMM00152308 CHEMBL1774084 Bioactive AGN-PC-035FIY
CFAMM00152325 CHEMBL1774078 Bioactive AGN-PC-035FKW
CFAMM00152318 CHEMBL1774071 Bioactive AGN-PC-035FEP
CFAMM00152307 CHEMBL1774085 Bioactive AGN-PC-035FJD
CFAMM00152324 CHEMBL1774077 Bioactive AGN-PC-00A9HD
CFAMM00152314 CHEMBL1774082 Bioactive AGN-PC-035FHL
CFAMM00152317 CHEMBL1774070 Bioactive AGN-PC-035FLP
CFAMM00152323 CHEMBL1774076 Bioactive AGN-PC-00DCSM
CFAMM00152313 CHEMBL1774083 Bioactive SureCN5374099
CFAMM00152329 CHEMBL1774067 Bioactive AGN-PC-035FFL
CFAMM00152322 CHEMBL1774075 Bioactive AGN-PC-0A9TYI
CFAMM00152311 CHEMBL1774081 Bioactive AGN-PC-035FFW
CFAMM00152321 CHEMBL1774074 Bioactive AGN-PC-035FFD
CFAMM00152310 CHEMBL1774086 Bioactive AGN-PC-00BH0U
CFAMM00152320 CHEMBL1774073 Bioactive AGN-PC-035FHA
CFAMM00152333 CHEMBL1774068 Bioactive SureCN5371648
CFAMM00152309 CHEMBL1774087 Bioactive SureCN4759674
CFAMM00152326 CHEMBL1774079 Bioactive SureCN5367118
CFAMM00152328 DCL000595 Clinical Trial Drug PF-217830

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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