CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD343
Family Name B-lymphocyte antigen CD20 Inhibitor Rituxan Immunology Family
No. of Seeds 10 No. of Other Members 17
Family Centroid CFAMM00152559 Functional Category Clinical Trial Drug
Superfamily High affinity nerve growth factor receptor Ligand Lestaurtinib Superfamily
Class Class 665

Cousin Family NamesSeedsMembers
High affinity nerve growth factor receptor Ligand Lestaurtinib... 6 126
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 4 1
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... 5 2
DNA topoisomerase 1 inhibitor EDOTECARIN family 3 35
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
Vascular endothelial growth factor receptor 2 and Angiopoietin... 14 0
Tyrosine-protein kinase JAK3 inhibitor CHEMBL234066 family 1 2
Protein kinase C alpha type and Protein kinase C delta type in... 2 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00152563 CHEMBL364347 Bioactive CHEMBL364347
CFAMM00152559 DCL000628 Clinical Trial Drug Rituxan Immunology
CFAMM00152561 DNC010451 Investigative Drug PKC-412
CFAMM00152554 DNC002782 Investigative Drug Staurosporine
CFAMM00152555 DNC001380 Investigative Drug Staurosporine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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