CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Ligand Abaperidone Family
No. of Seeds 6 No. of Other Members 159
Family Centroid CFAMM00153069 Functional Category Clinical Trial Drug with Natural Product
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Ligand Abaperidone Superfamily
Class Class 1054

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand Benzisoxazole Derivative Risperi... 3 32
Prostaglandin G/H synthase 2 Inhibitor Benzisoxazole Derivativ... 8 38
Cystic fibrosis transmembrane conductance regulator and Anocta... 12 74
Sodium-dependent dopamine transporter Inhibitor RTI-336 Family 21 61
Tyrosine-protein phosphatase non-receptor type 1 Ligand Compou... 10 174
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 11
Acetylcholinesterase and Cholinesterase inhibitor Icopezil mal... 10 14
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 4 10
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 3
Nuclear receptor subfamily 4 group A member 2 ligand 6-[4-(2-m... 2 33
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 4 1
Acetylcholinesterase inhibitor SureCN6987022 family 4 11
Peroxisome proliferator-activated receptor alpha and Peroxisom... 6 3
Estrogen receptor beta and Estrogen receptor ligand SureCN3933... 7 28
Peroxisome proliferator-activated receptor delta and Peroxisom... 3 17
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 1 0
5-hydroxytryptamine receptor 4 ligand 4-[[4-[[4-(2-methylpropo... 10 1
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 1 0
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 4
Nuclear receptor subfamily 4 group A member 2 and Metabotropic... 2 16
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 3 0
D(3) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 6 3
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Cytochrome P450 1A2 and Cytochrome P450 2C19 inhibitor AGN-PC-... 1 5
Menin and Histone-lysine N-methyltransferase 2A inhibitor CHEM... 1 2
Metabotropic glutamate receptor 2 ligand SureCN1996376 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00152977 CHEMBL14322 Bioactive SureCN1544927
CFAMM00153000 CHEMBL150412 Bioactive SureCN8133167
CFAMM00153006 CHEMBL14395 Bioactive SureCN1544863
CFAMM00152960 CHEMBL357035 Bioactive SureCN6355701
CFAMM00153069 DCL000673 Clinical Trial Drug Abaperidone hydrochloride
CFAMM00152998 DCL000843 Clinical Trial Drug Iloperidone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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