CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Urokinase-type plasminogen activator Inhibitor Amediplase Family
No. of Seeds 1 No. of Other Members 28
Family Centroid CFAMM00153331 Functional Category Clinical Trial Drug with Human Metabolite & Natural Product
Superfamily Urokinase-type plasminogen activator Inhibitor Amediplase Superfamily
Class Class 1057

Cousin Family NamesSeedsMembers
Glucokinase Inhibitor R7201 Family 22 105
Proto-oncogene tyrosine-protein kinase Src Inhibitor DPI59 Family 1 7
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Vitamin D3 receptor ligand (3E,5E)-6-[3-[2-[3,4-bis(hydroxymet... 2 33
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 4
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 18


External ID

Functional Category

Molecule Name

CFAMM00153331 DCL000691 Clinical Trial Drug Amediplase

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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