CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD368
Family Name D(2) dopamine receptor Ligand Aplindore Fumarate Family
No. of Seeds 2 No. of Other Members 30
Family Centroid CFAMM00153417 Functional Category Clinical Trial Drug
Superfamily D(2) dopamine receptor Ligand Aplindore Fumarate Superfamily
Class Class 1058

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand quinolone derivative Carteolol... 1 38
D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 2
Sodium-dependent serotonin transporter and D(2) dopamine recep... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 3 1
Trace amine-associated receptor 1 ligand EPPTB family 4 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 2 4
Motilin receptor ligand SureCN14564469 family 1 6
Galanin receptor type 3 and Alpha-1A adrenergic receptor ligan... 2 16
Cathepsin K inhibitor (1R,2R)-N-(cyanomethyl)-2-[4-(3-methoxyp... 2 1
Receptor-type tyrosine-protein kinase FLT3 ligand (3Z)-5-chlor... 1 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 4 4
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-(3-methoxy-2-me... 2 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 4 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 3 0
Methionine aminopeptidase 2 and Methionine aminopeptidase 1 in... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00153417 DCL000698 Clinical Trial Drug Aplindore fumarate
CFAMM00153408 DNC003837 Investigative Drug 4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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