CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD382
Family Name 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Ligand Bifeprunox Family
No. of Seeds 3 No. of Other Members 27
Family Centroid CFAMM00153938 Functional Category Clinical Trial Drug
Superfamily D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A Binder Superfamily
Class Class 1069

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Amyloid beta A4 protein Inhibitor SB-13 Family 1 2
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor ... 7 10
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 11 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 2 0
Translocator protein inhibitor [11C]DAA1106 family 15 2
Translocator protein inhibitor N-methyl-2-[2-oxo-5-[4-(trifluo... 9 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 0
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3... 2 1
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 2
Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[(4-hy... 1 5
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00153932 CHEMBL306634 Bioactive SureCN11929266
CFAMM00153938 DCL000724 Clinical Trial Drug Bifeprunox
CFAMM00153927 DCL000785 Clinical Trial Drug DU-127090

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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