CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD384
Family Name Synaptic vesicle glycoprotein 2A Inhibitor Brivaracetam Family
No. of Seeds 9 No. of Other Members 46
Family Centroid CFAMM00154102 Functional Category Clinical Trial Drug with Human Metabolite & Natural Product
Superfamily Synaptic vesicle glycoprotein 2A Inhibitor Brivaracetam Superfamily
Class Class 965

Cousin Family NamesSeedsMembers
Sodium channel protein type 1 subunit alpha Ligand Levetiracet... 7 56
Tubulin beta chain Inhibitor Tasidotin Family 1 1
Beta-2 adrenergic receptor Ligand GSK642444 Family 4 10
Chymase Inhibitor Bceab Family 5 22
Dipeptidyl peptidase 4 Inhibitor Fe 999011 Family 10 45
Neutrophil collagenase Inhibitor 3-amino-azacyclotridecan-2-on... 1 17
Dipeptidyl peptidase 4 and Seprase Inhibitor N-alkyl Gly-boro-... 6 11
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Alp... 4 18
Dipeptidyl peptidase 4 Inhibitor (s)-2-amino-1-azetidin-1-yl-2... 3 25
Dipeptidyl peptidase 4 and Seprase Inhibitor N-alkyl Gly-boro-... 6 4
Dipeptidyl peptidase 4 Inhibitor (s)-pyrrolidin-1-yl(pyrrolidi... 2 8
Sodium/glucose cotransporter 1 Inhibitor Qcpac Family 4 7
C-C chemokine receptor type 2 Ligand (s)-3-(2',2'-dimethyl-pro... 1 3
Chymotrypsin-like elastase family member 1 Inhibitor Acetyl-al... 3 12
Tripeptidyl-peptidase 2 Inhibitor (2s)-aminobutyryl-(r)-pipeco... 2 15
Alpha-galactosidase A Inhibitor AT1001 Family 1 0
Dipeptidyl peptidase 4 Inhibitor N-alkyl Gly-boro-pro Derivati... 2 8
Dipeptidyl peptidase 4 and Seprase Inhibitor N-alkyl Gly-boro-... 4 4
Histone deacetylase 4 and Histone deacetylase 1 inhibitor CHEM... 5 2
Calpain-1 catalytic subunit inhibitor (2S)-2-(methanesulfonami... 1 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 1 3
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 9 inhibitor [(... 5 3
Prothrombin inhibitor [1-[[(2S)-1-acetylpyrrolidine-2-carbonyl... 1 0
Dipeptidyl peptidase 4 inhibitor C5-substituted pyrrolidine 14... 1 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
Dipeptidyl peptidase 4 inhibitor (3S,5S)-5-[(2S)-2-cyanopyrrol... 11 13
Dipeptidyl peptidase 4 inhibitor 2-[(3R,5S)-5-[(2S)-2-cyanopyr... 4 2
Neutrophil elastase inhibitor cyclopentyl N-[(2S)-3-methyl-1-o... 2 2
Dipeptidyl peptidase 4 inhibitor AGN-PC-008GYG family 2 0
Dipeptidyl peptidase 2 inhibitor (2S)-1-[(3aR,6aR)-3,3a,4,5,6,... 1 0
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor (2... 1 0
Prolyl endopeptidase inhibitor SureCN3280014 family 1 1
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
Calpain-1 catalytic subunit inhibitor (2S)-2-(dimethylcarbamoy... 1 1
Piperidines Metabolite 3-Amino-2-piperidone Family 2 2
Peptides Metabolite L-prolyl-L-glycine Family 1 3
Piperazines Metabolite L-Cyclo(alanylglycyl) Family 2 8
Alkylamines Metabolite apo-[3-methylcrotonoyl-CoA:carbon-dioxi... 1 1
NP (s)-2-(1-((s)-2-amino-3-methylbutanoyl)piperidine-4-carboxa... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00154090 CHEMBL317488 Bioactive L-Prolyl-L-leucylglycinamide
CFAMM00154102 DCL000730 Clinical Trial Drug Brivaracetam
CFAMM00154146 DNC013234 Investigative Drug (2S)-aminobutyryl-L-proline-(2S)-methylbutylamide
CFAMM00154127 DNC013246 Investigative Drug L-valyl-L-prolinamide
CFAMM00154126 DNC013243 Investigative Drug L-norleucyl-L-prolinamide
CFAMM00154117 DNC013236 Investigative Drug (2S)-aminobutyryl-L-proline isobutylamide
CFAMM00154125 DNC013242 Investigative Drug L-leucyl-L-prolinamide
CFAMM00154123 DNC013248 Investigative Drug L-valyl-L-proline hexylamide
CFAMM00154137 DNC013241 Investigative Drug L-isoleucyl-L-prolinamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543