CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Integrin alpha-4 Inhibitor CDP323 Family
No. of Seeds 8 No. of Other Members 17
Family Centroid CFAMM00154247 Functional Category Clinical Trial Drug
Superfamily Integrin alpha-4 Inhibitor CDP323 Superfamily
Class Class 898

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
C-C chemokine receptor type 5 ligand AC1LA25C family 3 6
C-C chemokine receptor type 5 ligand (2R)-3-cyclobutyl-2-[(3S,... 9 4
A disintegrin and metalloproteinase with thrombospondin motifs... 1 3
C-C chemokine receptor type 5 ligand SureCN13543564 family 10 3
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
C-C chemokine receptor type 5 ligand (2R)-3-cyclobutyl-2-[(3S,... 2 0
Integrin alpha-4 inhibitor (2S)-2-[(2-bromo-3-oxospiro[3.5]non... 9 0


External ID

Functional Category

Molecule Name

CFAMM00154250 CHEMBL479346 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-[2-(6-chloropyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]propanoic acid
CFAMM00154246 CHEMBL481659 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00154255 CHEMBL449165 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-[2-[6-(trifluoromethyl)pyridin-3-yl]imidazo[4,5-b]pyridin-3-yl]phenyl]propanoic acid
CFAMM00154245 CHEMBL487439 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-piperidin-3-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00154261 CHEMBL486445 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-[2-[6-(methylamino)pyridin-3-yl]imidazo[4,5-b]pyridin-3-yl]phenyl]propanoic acid
CFAMM00154244 CHEMBL519075 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-piperidin-2-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00154253 CHEMBL471303 Bioactive (2S)-2-[(2-bromo-4,4-dimethyl-3-oxocyclobuten-1-yl)amino]-3-[4-(2-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00154247 DCL000743 Clinical Trial Drug CDP323

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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