CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD4
Family Name 72 kDa type IV collagenase and Interstitial collagenase Inhibitor Prinomastat Family
No. of Seeds 5 No. of Other Members 81
Family Centroid CFAMM00126754 Functional Category Clinical Trial Drug with Natural Product
Superfamily 72 kDa type IV collagenase and Interstitial collagenase Inhibitor Prinomastat Superfamily
Class Class 816

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 11
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(4-f... 2 5
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 1 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-hydro... 3 25
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
Disintegrin and metalloproteinase domain-containing protein 17... 1 3
Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N... 4 1
Collagenase 3 and A disintegrin and metalloproteinase with thr... 5 6
5-hydroxytryptamine receptor 6 ligand SureCN5253197 family 4 2
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 2
Prothrombin inhibitor AGN-PC-074A4O family 2 7
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 2 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 1 3
Collagenase 3 and Stromelysin-1 inhibitor (2R,4S)-N-hydroxy-4-... 1 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Oxytocin receptor and Vasopressin V1a receptor ligand 4-methox... 9 8
Menin and Histone-lysine N-methyltransferase 2A inhibitor 3-{4... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
DNA-(apurinic or apyrimidinic site) lyase and Alkaline phospha... 1 2
Thromboxane-A synthase inhibitor AGN-PC-00FAD1 family 2 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 0
Prothrombin inhibitor AGN-PC-073FOY family 2 1
Pol polyprotein inhibitor AC1LASR0 family 2 1
Prothrombin inhibitor tert-butyl N-[2-[3-[bis(benzenesulfonyl)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00126704 CHEMBL194570 Bioactive AGN-PC-075XNM
CFAMM00126675 CHEMBL114158 Bioactive N-hydroxy-4-[(4-pyridin-4-yloxyphenyl)sulfonylamino]oxane-4-carboxamide
CFAMM00126754 DCL000004 Clinical Trial Drug Prinomastat
CFAMM00126770 DNC000955 Investigative Drug MMI270
CFAMM00126691 DNC000169 Investigative Drug AG3340

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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