CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD40
Family Name Farnesyltransferase beta subunit, putative Inhibitor AZD3409 Family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00130165 Functional Category Clinical Trial Drug
Superfamily secretase and Farnesyltransferase beta subunit, putative Binder Superfamily
Class Class 845

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 17 14
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00130163 CHEMBL53670 Bioactive propan-2-yl (2S)-2-[[2-[2-(4-fluorophenyl)ethyl]-5-[[(2S,4S)-4-(pyridine-3-carbonylsulfanyl)pyrrolidin-2-yl]methylamino]benzoyl]amino]-4-methylsulfanylbutanoate
CFAMM00130165 DCL000061 Clinical Trial Drug AZD3409

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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