CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD404
Family Name Adenosine receptor A2a Ligand Dexefaroxan Family
No. of Seeds 11 No. of Other Members 46
Family Centroid CFAMM00155530 Functional Category Clinical Trial Drug with Human Metabolite
Superfamily Adenosine receptor A2a and Alpha-2 adrenergic receptor Binder Superfamily
Class Class 1080

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor ligand Clonidine derivative Lofexi... 2 2
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha-2 adrenergic receptor Ligand Idazoxan Family 6 26
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 10 8
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00155574 CHEMBL1276218 Bioactive 2-[1-(2-cyclopropylphenoxy)ethyl]-4,5-dihydro-1H-imidazole
CFAMM00155567 CHEMBL1956195 Bioactive CYCLOMETHYLINE
CFAMM00155546 CHEMBL13852 Bioactive cirazoline
CFAMM00155560 CHEMBL541870 Bioactive AGN-PC-07C2EX
CFAMM00155550 CHEMBL554430 Bioactive AGN-PC-07C0IC
CFAMM00155556 CHEMBL495096 Bioactive 2-[1-(2-cyclopentylphenoxy)ethyl]-4,5-dihydro-1H-imidazole
CFAMM00155570 CHEMBL2089156 Bioactive 2-[(1S)-1-[2-(cyclopropylmethyl)phenoxy]ethyl]-4,5-dihydro-1H-imidazole
CFAMM00155536 CHEMBL1276220 Bioactive 2-[(1S)-1-(2-cyclopropylphenoxy)ethyl]-4,5-dihydro-1H-imidazole
CFAMM00155575 CHEMBL539313 Bioactive Efaroxan hydrochloride
CFAMM00155528 CHEMBL542760 Bioactive AGN-PC-07C0JO
CFAMM00155530 DCL000771 Clinical Trial Drug Dexefaroxan

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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