CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD420
Family Name Growth hormone receptor Ligand EP-51216 Family
No. of Seeds 34 No. of Other Members 390
Family Centroid CFAMM00156779 Functional Category Clinical Trial Drug with Natural Product
Superfamily Growth hormone receptor Binder Superfamily
Class Class 71

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... 4 151
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
Alpha adrenergic receptor ligand ergot alkaloid Dihydroergota... 7 12
Alpha-2 adrenergic receptor Ligand Yohimbine Family 7 52
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Epidermal Growth Factor family 111 209
HIV protease Inhibitor Indinavir Family 36 211
HIV protease Inhibitor Saquinavir Family 64 428
Reverse transcriptase Inhibitor Delavirdine Family 1 68
5-hydroxytryptamine receptor 1D Ligand Rizatriptan Family 7 460
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259
D(2) dopamine receptor Ligand Sertindole Family 3 173
Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209
Gamma-aminobutyric acid A receptor Ligand Bromazepam Family 2 60
Histamine H1 receptor Ligand Triprolidine Family 19 316
Renin Inhibitor Remikiren Family 100 126
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Bacterial outer membrane Inhibitor Daptomycin Family 6 50
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
Prothrombin Inhibitor Ximelegatran Family 8 157
Prothrombin Inhibitor Dabigatran Family 7 182
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Histidine decarboxylase Inhibitor Bf-derm1 Family 12 95
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Neuromedin-K receptor Ligand SB222200 Family 17 235
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Substance-P receptor Ligand GSK424887 Family 8 184
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Reverse transcriptase Inhibitor IDX899 Family 2 118
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Substance-P receptor Ligand TAK-637 Family 18 63
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
NS5A protein Inhibitor Bms 790052 Family 5 9
BIBT986 family 7 96
Amg 423 family 7 47
Setipiprant family 5 118
CBP-501 family 7 8
Histone deacetylase Inhibitor JNJ-26481585 Family 2 5
ABC294640 family 5 75
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
CP-18770 family 6 27
Gonadotropin-releasing hormone Inhibitor ASP3550 Family 33 60
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Family 6 29
Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
Lethal factor Inhibitor GM6001 Family 50 435
XL-888 family 16 85
Cyclin-dependent kinase 5 Inhibitor 9-nitropaullone Family 2 13
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... 4 25
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
Arachidonate 5-lipoxygenase Inhibitor Ici 207968 Family 3 7
Class II cytokine receptor Ligand IL-10 Family 7 45
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 16 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Dihydroorotate dehydrogenase Inhibitor Nsc 665564 Family 2 83
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
C-X-C chemokine receptor type 2 Ligand Sb 272844 Family 7 3
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 3 15
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Cathepsin B and Cathepsin K Inhibitor Z-arg-leu-val-agly-ile-v... 3 19
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 5 Inhibi... 2 5
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... 3 5
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Cyclin-dependent kinase 1 and G2/mitotic-specific cyclin-B1 In... 2 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Histone deacetylase 6 Inhibitor N-(quinolin-3-yl)-6-(sulfamoyl... 4 8
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Cannabinoid receptor 2 Ligand JWH-249 Family 7 13
Gonadotropin-releasing hormone receptor Ligand Azaline B Family 12 0
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Indoleamine 2,3-dioxygenase 1 Inhibitor N-[2-(indol-3-yl)ethyl... 2 2
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Platelet-derived growth factor receptor alpha and Platelet-der... 3 3
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Gonadotropin-releasing hormone receptor Ligand [d-ncy(methyl)4... 32 0
Serine/threonine-protein kinase Chk1 Inhibitor BIS-IMIDE A Family 1 3
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Mineralocorticoid receptor and Androgen receptor Ligand WAY-25... 10 26
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Poly [ADP-ribose] polymerase 1 Inhibitor 3-ethenylquinoline-8-... 8 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 4 33
5-hydroxytryptamine receptor 2C Ligand Cyclo[(6-bromotryptopha... 3 17
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Angiotensin-converting enzyme and Endothelin-converting enzyme... 2 10
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Serine/threonine-protein kinase mTOR Inhibitor 4-(2-(1h-indol-... 2 15
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Kinesin-like protein KIF11 Inhibitor 2-(trifluoromethyl)-9h-ca... 5 0
Kinesin-like protein KIF11 Inhibitor 9h-carbazole-2-carbaldehy... 1 3
Adenosine receptor A3 and Potassium voltage-gated channel subf... 1 18
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand N-(9h-... 5 2
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 10 18
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 7,12-d... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Glutamate receptor 1 Ligand Piriqualone Family 8 67
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Amine oxidase [flavin-containing] A Inhibitor N-benzyl-1h-pyrr... 12 46
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase Inhibitor Infractopicrin Family 1 1
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Histone deacetylase Inhibitor ST-5732 Family 8 6
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 46 0
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Cycl... 7 6
Substance-K receptor ligand 1-N,2-N-bis[2-(1H-indol-3-yl)ethyl... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Huntingtin and Glycogen synthase kinase-3 beta inhibitor SB 21... 2 4
Prothrombin inhibitor SureCN5856722 family 3 16
Pol polyprotein inhibitor penicillin deriv. 71 family 1 2
C-C chemokine receptor type 5 ligand AC1LAJEM family 4 14
Pol polyprotein inhibitor penicillin deriv. 40 family 2 4
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Rho-associated protein kinase 2 and cAMP-dependent protein kin... 2 7
Deoxycytidine kinase inhibitor N-[(1S,3S)-3-(4-amino-5-fluoro-... 2 5
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... 2 14
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 17 14
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 2 1
Cathepsin K inhibitor [(3S)-1-(1H-indole-6-carbonyl)-4,4-dimet... 2 4
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA4D family 1 0
Prolyl endopeptidase inhibitor [(2S,3aS,7aS)-2-(pyrrole-1-carb... 2 0
Histone deacetylase 3 and Histone deacetylase 6 inhibitor Tria... 20 37
Calcitonin gene-related peptide type 1 receptor ligand CHEMBL1... 5 8
Cholecystokinin receptor type A ligand A-65186 family 2 6
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 6 2
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Pol polyprotein inhibitor N-[(2S)-1-[[(2S,3R,4S,5S)-3,4-dihydr... 2 0
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 5 0
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 7 58
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 17 28
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 14 8
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22
Cathepsin L1 inhibitor Bio2_000267 family 9 1
Neutrophil collagenase and Stromelysin-3 inhibitor AC1MORIH fa... 7 9
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 1 0
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 0
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 28 9
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 13 3
Vascular endothelial growth factor receptor 2 and Receptor-typ... 7 4
Prolyl endopeptidase inhibitor SureCN8938520 family 2 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 13
Substance-P receptor ligand N-[(1S,2R)-2-[[(1R)-1-[methyl-(2-p... 2 0
Serine/threonine-protein kinase D1 inhibitor SureCN1424142 family 13 8
Caspase-1 inhibitor (3S)-3-[[(2S)-4-[2-(1,2-dimethylindol-3-yl... 3 4
Caspase-1 inhibitor (3S)-4-oxo-3-[[(2S)-4-oxo-2-propan-2-yl-4-... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 11
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 10 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1233942 ... 6 0
Serine/threonine-protein kinase pim-3 and Serine/threonine-pro... 4 6
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
Lysosomal Pro-X carboxypeptidase inhibitor N-[(2S)-1-[(2S)-2-(... 1 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 0
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... 5 2
Histamine H3 receptor ligand AGN-PC-04YWRD family 5 13
Cathepsin K inhibitor SureCN2155973 family 3 1
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 1
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 1 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 4 53
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Coagulation factor X and Trypsin-1 inhibitor 2-(5-carbamimidoy... 5 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 3
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 0
5-hydroxytryptamine receptor 1A ligand 2-[4-(quinolin-2-ylmeth... 2 91
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 2 5
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
Thyroid hormone receptor beta and Microtubule-associated prote... 1 8
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
Disintegrin and metalloproteinase domain-containing protein 17... 4 0
Disintegrin and metalloproteinase domain-containing protein 17... 3 3
Growth hormone-releasing hormone receptor ligand ethyl (1S)-1'... 3 2
Somatostatin receptor type 2 ligand (2R,3S)-N-[(5-amino-1,3-di... 2 5
Prelamin-A/C and Pyruvate kinase PKM inhibitor CHEMBL1481187 f... 1 7
Mitogen-activated protein kinase 1 and Nonstructural protein 1... 1 33
Survival motor neuron protein and Menin inhibitor CHEMBL151109... 1 11
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 5 8
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 0
Somatostatin receptor type 4 ligand methyl 5-(diaminomethylide... 2 34
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 2 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Peptide deformylase inhibitor (2R)-N-[(2S)-3,3-dimethyl-1-oxo-... 2 1
Platelet-activating factor receptor ligand YM-461 family 1 11
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 10 9
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 5 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 1
Serine/threonine-protein kinase D3 and Protein kinase C delta ... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... 4 2
Dipeptidyl peptidase 4 inhibitor (2S)-1-[2-[5-(aminomethyl)-2-... 4 4
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Glycogen synthase kinase-3 beta and Tyrosine-protein kinase JA... 1 0
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Translocator protein inhibitor AGN-PC-08WI0V family 1 0
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Insulin-like growth factor 1 receptor ligand AGN-PC-09QGLU family 3 1
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Substance-K receptor ligand N-[1-[[(2S)-1-[[1-(oxan-4-ylmethyl... 3 0
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... 2 0
Coagulation factor X inhibitor SureCN4172349 family 7 3
Gonadotropin-releasing hormone receptor and Cytochrome P450 3A... 5 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... 3 1
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 18 3
Endothelin-1 receptor and Endothelin B receptor ligand SureCN9... 3 10
Prothrombin and Trypsin-1 inhibitor 1-[2-(4-benzylpiperidin-1-... 2 2
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 4 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Baculoviral IAP repeat-containing protein 2 and Baculoviral IA... 1 0
Prostaglandin D2 receptor 2 ligand SureCN2189431 family 7 1
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Histone deacetylase 4 and Histone deacetylase 3 inhibitor 4-az... 2 1
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 5 1
Renin and Potassium voltage-gated channel subfamily H member 2... 9 2
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 1 0
Mitogen-activated protein kinase 9 and MAP kinase-activated pr... 1 0
Glycogen synthase kinase-3 beta inhibitor 3-(2-bromoacetyl)-4-... 1 0
C-X-C chemokine receptor type 3 ligand (6aR,9R)-N-phenyl-4-(2-... 5 0
Smoothened homolog inhibitor (8aS)-N-[2-(3-cyanophenyl)pyridin... 3 4
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 0
Renin inhibitor [2-[(3-fluoro-2-methylphenyl)methyl]-6-methyl-... 2 1
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 3
Cannabinoid receptor 2 ligand 1-[[4-[5-fluoro-6-(piperidin-1-y... 21 2
Histamine H3 receptor ligand N-methyl-N-[(3R)-1-propan-2-ylpyr... 3 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL186461 family 2 4
Cytochrome P450 2D6 and Cytochrome P450 2C19 inhibitor Demethy... 1 4
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
Renin and Potassium voltage-gated channel subfamily H member 2... 13 11
Histamine H1 receptor and Histamine H4 receptor ligand [4-[2-[... 1 1
Substance-P receptor and Neuromedin-K receptor ligand 2-[3,5-b... 7 0
Heat shock protein HSP 90-beta inhibitor N-[(9R)-4-(3H-imidazo... 1 0
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[2-(1H-ind... 1 0
Rho-associated protein kinase 2 and Rho-associated protein kin... 2 6
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
Coagulation factor X inhibitor SureCN8289965 family 4 5
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Melanin-concentrating hormone receptor 2 ligand N-[(1R)-1'-(9H... 4 1
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
3-phosphoinositide-dependent protein kinase 1 and RAC-alpha se... 10 4
Translocator protein inhibitor N,N-diethyl-11-(2-fluoroethyl)-... 14 9
Cathepsin L1 and Cathepsin S inhibitor N-[(2S)-4-methyl-1-oxo-... 3 3
Cannabinoid receptor 1 ligand (2-cyclopentyl-5-prop-2-enyl-3,4... 3 8
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 3 1
Histamine H3 receptor ligand 1-[4-(1H-imidazol-5-ylmethyl)pipe... 1 2
Adenosine receptor A2b and Adenosine receptor A2a ligand N-(4-... 2 14
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 3 5
Dipeptidyl peptidase 4 inhibitor 2-[[2-[(3R)-3-aminopiperidin-... 1 0
Substance-P receptor ligand [3,5-bis(trifluoromethyl)phenyl]-[... 17 1
Cannabinoid receptor 1 ligand N-[2-(cyclopropylamino)-2-oxoeth... 5 5
Relaxin-3 receptor 1 and Relaxin-3 receptor 2 ligand CHEMBL203... 4 1
Hematopoietic prostaglandin D synthase inhibitor 4-(3-methylis... 1 7
High affinity nerve growth factor receptor and BDNF/NT-3 growt... 4 3
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
Egl nine homolog 1 inhibitor 1'-[(3-methylpyridin-2-yl)methyl]... 6 4
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-quinolin-4-ylpi... 5 8
Prothrombin and Tissue-type plasminogen activator inhibitor 2-... 4 5
Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... 2 2
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
Melanin-concentrating hormone receptor 1 ligand N-[(3S)-1-[[(3... 2 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 0
Growth hormone secretagogue receptor type 1 ligand SureCN36660... 4 14
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1-phenylimidaz... 2 1
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152412 family 8 0
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Di... 2 3
Cathepsin K inhibitor (1R,2R)-2-(6-chloro-1,3,4,5-tetrahydropy... 2 0
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(1-cyanocyclop... 10 7
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... 2 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Glutamate receptor ionotropic, NMDA 2B ligand N-[3-[2-(4-benzy... 2 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Prostaglandin D2 receptor 2 ligand 2-[(3R)-3-(3,3-diphenylprop... 1 0
Neuromedin-K receptor and Potassium voltage-gated channel subf... 13 2
Vascular endothelial growth factor receptor 2 and Angiopoietin... 14 0
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 6 8
Somatostatin receptor type 3 and Somatostatin receptor type 4 ... 5 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206058 family 5 0
Serine/threonine-protein kinase Chk1 inhibitor 3-[5-(piperidin... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547533 f... 3 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN5551829 f... 1 14
Dual specificity protein kinase CLK4 and Mitogen-activated pro... 1 1
Coagulation factor X and Prothrombin inhibitor SureCN8237487 f... 16 1
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Cannabinoid receptor 1 and Cytochrome P450 3A4 ligand N-(oxan-... 2 0
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 2 0
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
Translocator protein inhibitor CHEMBL2331870 family 2 0
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Disintegrin and metalloproteinase domain-containing protein 17... 7 9
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 3 4
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Motilin receptor ligand SureCN2768052 family 3 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 4
Gonadotropin-releasing hormone receptor ligand (3S)-3-[[(2R)-2... 1 0
Coagulation factor X inhibitor ethyl (3R,4S)-3-[(3-chloro-1H-i... 5 0
C-C chemokine receptor type 2 ligand 2-[4-(5-amino-1H-indol-3-... 3 2
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0
Seprase and Prolyl endopeptidase inhibitor 7-chloro-N-[2-[(2S)... 3 3
Gastrin/cholecystokinin type B receptor ligand CHEMBL2386886 f... 1 0
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Leucine-rich repeat serine/threonine-protein kinase 2 and Plat... 1 0
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3-fluo... 6 4
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 8
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... 2 0
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 2 1
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 1
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Histone deacetylase 1 inhibitor (2S)-N'-hydroxy-2-(pyridine-2-... 3 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 2 2
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 0
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 18
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 5
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 8
Somatostatin receptor type 5 ligand L-817,818 family 2 0
C-C chemokine receptor type 2 ligand SureCN5947024 family 11 0
High affinity nerve growth factor receptor ligand CHEMBL254555... 2 2
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 4
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 2 2
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 1
Gonadotropin-releasing hormone receptor ligand (3S)-3-[[(2S)-2... 5 0
Renin inhibitor tert-butyl N-[1-[[1-[[1-cyclohexyl-4,4-difluor... 5 0
Gastrin-releasing peptide receptor ligand (2S)-N-[(2S)-1-[[(2S... 1 0
Proteinase-activated receptor 1 and Prothrombin ligand (2S)-N-... 3 23
Gonadotropin-releasing hormone receptor ligand 1-[2-(3,5-dimet... 3 0
Protein kinase C delta type and Protein kinase C beta type inh... 4 4
CGMP-dependent protein kinase inhibitor 1-[4-acetyl-3-[[4-[5-(... 2 0
Endothelin B receptor and Endothelin-1 receptor ligand 2-[[(2R... 17 10
5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine recept... 2 0
Neutrophil collagenase and Stromelysin-3 inhibitor [3-[[1-amin... 3 2
Growth factor receptor-bound protein 2 ligand 2-[4-[(2S)-3-[[1... 1 0
Substance-P receptor ligand AGN-PC-004REJ family 3 0
Gastrin/cholecystokinin type B receptor ligand (2R)-2-[[5-(8-a... 2 3
5-hydroxytryptamine receptor 1D ligand N-[4-[[5-[[3-(2-aminoet... 8 7
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... 3 0
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 8 5
Bombesin receptor subtype-3 ligand SureCN13887096 family 3 1
Platelet-activating factor receptor ligand (1-ethylindol-3-yl)... 17 13
Tyrosine-protein kinase Yes and Proto-oncogene tyrosine-protei... 7 18
Platelet-activating factor receptor ligand N,N-diethyl-3-[(4R)... 11 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
Neprilysin and Endothelin-converting enzyme 1 inhibitor (2S)-2... 5 0
Platelet-activating factor receptor ligand (4R)-N-(3-benzoylph... 2 1
Endothelin-1 receptor and Endothelin B receptor ligand 2-[[(2R... 5 3
Neutrophil collagenase and Interstitial collagenase inhibitor ... 1 0
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 6 4
Stromelysin-3 and Neutrophil collagenase inhibitor AGN-PC-074N... 3 1
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
Substance-P receptor and Substance-K receptor ligand N-methyl-... 2 2
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 2
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 3 1
Gonadotropin-releasing hormone receptor ligand methyl 4-[2-[[(... 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 2 1
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
Growth factor receptor-bound protein 2 ligand [4-[(2S)-2-aceta... 5 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
KiSS-1 receptor ligand SureCN5132924 family 2 4
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 1 0
Gonadotropin-releasing hormone receptor ligand 1-[2-(3,5-dimet... 2 0
C-X-C chemokine receptor type 2 and Cytochrome P450 2C9 ligand... 1 7
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 2 0
72 kDa type IV collagenase and Interstitial collagenase inhibi... 1 1
Angiotensin-converting enzyme inhibitor AC1L1IZN family 2 2
KiSS-1 receptor ligand N-[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-... 1 0
Coagulation factor X and Prothrombin inhibitor N,1-bis[(3-carb... 1 1
Sodium-dependent serotonin transporter and D(2) dopamine recep... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor SureCN4998361 family 1 1
CGMP-dependent protein kinase inhibitor AGN-PC-0761UG family 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Somatostatin receptor type 4 and Somatostatin receptor type 5 ... 3 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 5 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Coagulation factor X inhibitor 3-chloroindole compound, 20 family 4 5
Translocator protein inhibitor N,N-dibutyl-2-(7-chloro-2-pheny... 3 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 4
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4
Melanocortin receptor 3 and Melanocyte-stimulating hormone rec... 2 3
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 0
Melanin-concentrating hormone receptor 1 ligand SureCN4917950 ... 3 5
5-hydroxytryptamine receptor 7 ligand AGN-PC-00PFK0 family 1 0
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0
Mitogen-activated protein kinase 1 and Aurora kinase A inhibit... 16 3
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0
Interstitial collagenase and Stromelysin-1 inhibitor CHEMBL887... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 1
Translocator protein inhibitor CHEMBL1672413 family 1 2
Heat shock protein HSP 90-alpha inhibitor CHEMBL1760611 family 19 25
Kinesin-like protein KIF11 inhibitor 9-(trifluoromethyl)-1,2,4... 4 1
Substance-P receptor ligand methyl 6-acetamido-3-[[(2S)-1-[[3,... 1 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand CHE... 1 1
Potassium voltage-gated channel subfamily A member 5 and Volta... 2 4
Prolyl endopeptidase inhibitor 4-phenyl-1-[(2S,4S)-4-(4-pyridi... 2 1
P2X purinoceptor 7 inhibitor SureCN1194877 family 1 6
Serine/threonine-protein kinase Chk1 inhibitor SureCN6080935 f... 1 0
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 1 6
Neprilysin inhibitor AGN-PC-073PUZ family 1 0
Granzyme B inhibitor SureCN5917262 family 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL3... 1 9
Receptor-interacting serine/threonine-protein kinase 1 ligand ... 1 11
Peptide deformylase and Peptide deformylase 1A, chloroplastic/... 1 1
Histone deacetylase 1 and Histone deacetylase 2 inhibitor (2S)... 3 0
Cytochrome P450 2C9 and Cytochrome P450 3A4 inhibitor AGN-PC-0... 3 0
Insulin receptor ligand 2,5-dihydroxy-3-(1H-indol-3-yl)-6-phen... 1 0
Coagulation factor X inhibitor (3R,4R)-3-N-[2-fluoro-4-(2-oxop... 1 0
Nonstructural protein 1 and Lysine-specific demethylase 4E inh... 1 0
Proto-oncogene tyrosine-protein kinase Src and Epidermal growt... 3 1
Protein-glutamine gamma-glutamyltransferase 2 inhibitor SureCN... 2 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 0
Probable G-protein coupled receptor 142 ligand (2S)-2-[[(2R)-o... 1 0
Cytochrome P450 2C19 and Cytochrome P450 3A4 inhibitor (E)-3-[... 4 0
Prostaglandin D2 receptor 2 ligand AGN-PC-00QBAU family 1 24
Histone deacetylase 1 inhibitor N-[(2S)-1,8-dioxo-1-[2-(2-phen... 2 0
Tyrosine-protein kinase JAK3 inhibitor (3Z)-5-pyridin-3-yl-3-(... 1 0
Cyclin-dependent kinase 2 inhibitor pyrrollylactam indolinone ... 1 0
Proto-oncogene Wnt-3 inhibitor CHEMBL563202 family 2 0
Malate dehydrogenase, mitochondrial inhibitor AGN-PC-0796ZJ fa... 1 0
12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]i... 11 0
12b-methyl-2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]i... 16 0
(S)-2-amino-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4... 1 0
2,3,6,7-tetrahydropyrazino[1',2':1,2]pyrido[3,4-b]indole-1,4(1... 3 0
9H-pyrido[3,4-b]indole-3-carboxamide NP (1-(3-bromophenyl)-9h-... 5 0
(4aR,13bS,14aR)-3,4,4a,5,7,8,13,13b,14,14a-decahydro-5,14-etha... 2 0
6-(3-nitrophenyl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyri... 16 0
NP Agn-pc-099dao Family 2 0
8'-fluoro-6'-methyl-2,3,4,5',6',9-hexahydrodispiro[beta-carbol... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00156779 DCL000796 Clinical Trial Drug EP-51216
CFAMM00156697 DNC009723 Investigative Drug Ac-D-pro-L-Phe-D-trp-L-Phe-NH2
CFAMM00156877 DNC006269 Investigative Drug c[Nle-Arg-D-Phe-Arg-Trp-Glu]-NH2
CFAMM00156843 DNC006277 Investigative Drug c[Nle-Val-D-Phe-Arg-Trp-Glu]-NH2
CFAMM00156726 DNC009715 Investigative Drug c[L-Phe-D-pro-L-Phe-D-trp]
CFAMM00156632 DNC008572 Investigative Drug rPKPfQwFwLL-NH2
CFAMM00156696 DNC009722 Investigative Drug c[L-Ala-D-pro-L-Phe-D-trp]
CFAMM00156876 DNC006265 Investigative Drug c[Nle-Nle-D-Nal(2')-Arg-Trp-Glu]-NH2
CFAMM00156821 DNC008095 Investigative Drug c[CO-o-C6H4-CO-Pro-D-Phe-Arg-Trp-Lys]-NH2
CFAMM00156631 DNC008577 Investigative Drug DprwFwLL-NH2
CFAMM00156695 DNC009724 Investigative Drug Ac-L-Phe-D-trp-L-Phe-D-pro-NH2
CFAMM00156893 DNC003899 Investigative Drug MK-10
CFAMM00156875 DNC006267 Investigative Drug c[Nle-Arg-D-Nal(2')-Arg-Trp-Glu]-NH2
CFAMM00156999 DNC012382 Investigative Drug SPANTIDE
CFAMM00156630 DNC008575 Investigative Drug AwFwLL-NH2
CFAMM00156917 DNC014381 Investigative Drug Ac-[CFWKFC]-NH2
CFAMM00157060 DNC008580 Investigative Drug KwFwLL-NH2
CFAMM00156620 DNC000005 Investigative Drug (2R)-2-methyl-4-deoxy and 2,4-dideoxy
CFAMM00156629 DNC008574 Investigative Drug QwFwLL-NH2
CFAMM00156846 DNC006273 Investigative Drug c[Nle-Pro-D-Nal(2')-Arg-Trp-Glu]-NH2
CFAMM00156923 DNC008094 Investigative Drug c[CO-(CH2)3-CO-Pro-D-Phe-Arg-Trp-Lys]-NH2
CFAMM00156933 DNC006888 Investigative Drug Ac-Phe-[Orn-Pro-cha-Trp-Arg]
CFAMM00156635 DNC008579 Investigative Drug RwFwLL-NH2
CFAMM00156890 DNC006278 Investigative Drug c[Nle-Pro-D-Phe-Arg-Trp-Glu]-NH2
CFAMM00157059 DNC008581 Investigative Drug wFwLL-NH2
CFAMM00157014 DNC012660 Investigative Drug N-Hexyl-2-(2-phenyl-1H-indol-3-yl)-acetamide
CFAMM00156989 DNC012654 Investigative Drug N,N-Dihexyl-2-(2-phenyl-1H-indol-3-yl)-acetamide
CFAMM00156831 DNC000645 Investigative Drug FGIN-1-27
CFAMM00156818 DNC008092 Investigative Drug c[CO-(CH2)2-CO-Nle-D-Phe-Arg-Trp-Lys]-NH2
CFAMM00156845 DNC006270 Investigative Drug c[Nle-Gln-D-Phe-Arg-Trp-Glu]-NH2
CFAMM00156634 DNC008578 Investigative Drug HwFwLL-NH2
CFAMM00156844 DNC006276 Investigative Drug c[Nle-Nle-D-Phe-Arg-Trp-Glu]-NH2
CFAMM00156727 DNC009714 Investigative Drug c[L-Phe-D-pro-L-Phe-L-trp]
CFAMM00156633 DNC008573 Investigative Drug wFwGG-NH2

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22645 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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Computer-aided Drug Design
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