CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Purine nucleoside phosphorylase Inhibitor Forodesine Family
No. of Seeds 11 No. of Other Members 54
Family Centroid CFAMM00130618 Functional Category Clinical Trial Drug
Superfamily Purine nucleoside phosphorylase Inhibitor Forodesine Superfamily
Class Class 848

Cousin Family NamesSeedsMembers
Purine nucleoside phosphorylase inhibitor 6-[(2S,3S,4S,5R)-3,4... 1 0
S-methyl-5'-thioadenosine phosphorylase inhibitor 1-[(4-amino-... 7 1
Purine nucleoside phosphorylase inhibitor [6-(2-amino-4-oxo-1,... 5 3


External ID

Functional Category

Molecule Name

CFAMM00130610 CHEMBL522278 Bioactive SureCN1415524
CFAMM00130626 CHEMBL489691 Bioactive SureCN1415623
CFAMM00130617 CHEMBL522757 Bioactive SureCN1946264
CFAMM00130631 CHEMBL522099 Bioactive SureCN1415711
CFAMM00130591 CHEMBL516050 Bioactive SureCN1415816
CFAMM00130604 CHEMBL475537 Bioactive SureCN1415434
CFAMM00130595 CHEMBL490285 Bioactive SureCN1415688
CFAMM00130618 DCL000117 Clinical Trial Drug Forodesine
CFAMM00130576 DCL000065 Clinical Trial Drug BCX-4208
CFAMM00130632 DNC000791 Investigative Drug Immucillin-G
CFAMM00130569 DNC000268 Investigative Drug Aza-C-nucleosides

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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