CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD437
Family Name Interleukin-1 beta and Interleukin-6 Inhibitor Ibudilast Family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00157506 Functional Category Clinical Trial Drug
Superfamily Interleukin-6 and Interleukin-1 beta Binder Superfamily
Class Class 1101

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Hepatocyte growth factor receptor Ligand MK-8033 Family 19 42
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(4) dopamine receptor Ligand SPI-376 Family 7 84
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 4
Adenosine receptor A1 and Adenosine receptor A2a Ligand FK-838... 4 19
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Cannabinoid receptor 2 Ligand JWH-249 Family 7 13
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 5 22
Aldose reductase Inhibitor 3-(3-benzoyl-1h-pyrrol-1-yl)propano... 3 7
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-09M6D1 family 2 5
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Hepatocyte growth factor receptor ligand 9-[[3-methoxypropyl(m... 17 2
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(2-meth... 7 9
Histamine H3 receptor ligand N-methyl-N-[(3R)-1-propan-2-ylpyr... 3 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 1
D(3) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 2 0
Nuclear receptor ROR-gamma and Ras-related protein Rab-9A liga... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00157506 DCL000838 Clinical Trial Drug Ibudilast
CFAMM00157504 DNC000164 Investigative Drug AE-3763

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26382 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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