CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD439
Family Name Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibitor ITF2357 Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00157545 Functional Category Clinical Trial Drug
Superfamily Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Binder Superfamily
Class Class 271

Cousin Family NamesSeedsMembers
Sodium channel protein type 10 subunit alpha Ligand Tetracaine... 6 166
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Retinal dehydrogenase 1 and Menin inhibitor CHEMBL1507858 family 1 6
Neuropeptide Y receptor type 5 ligand SureCN3382773 family 1 13
Glucocorticoid receptor and Progesterone receptor ligand AGN-P... 2 9
Bifunctional epoxide hydrolase 2 inhibitor 6-[[1-(2,4-dimethyl... 1 3
Sodium-dependent serotonin transporter and D(2) dopamine recep... 8 6
Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y... 7 22
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Histone deacetylase 1 and Histone deacetylase 2 inhibitor Sure... 1 4
Protein farnesyltransferase subunit beta and Protein farnesylt... 2 4
Multidrug resistance protein 1 inhibitor [(2R,3S,4R)-4-[[(2S)-... 1 5
NP Methyl 3-acetyl-4-oxo-1,4-dihydroquinoline-8-carboxylate Fa... 2 0
Putative NP ZINC12659473 Family 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00157548 CHEMBL1213492 Bioactive Givinostat
CFAMM00157545 DCL000852 Clinical Trial Drug ITF2357

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22932 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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