CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor 3A Ligand KB-6806 Family
No. of Seeds 12 No. of Other Members 11
Family Centroid CFAMM00157553 Functional Category Clinical Trial Drug
Superfamily 5-hydroxytryptamine receptor 3A Ligand KB-6806 Superfamily
Class Class 171

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Nemonapride Family 70 283
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
5-hydroxytryptamine receptor 4 Ligand SB-207710 Family 10 5
D(2) dopamine receptor Ligand Epidepride Family 31 66
5-hydroxytryptamine receptor 4 ligand 2-(4-pyridin-4-ylpiperaz... 2 1
5-hydroxytryptamine receptor 4 ligand RS100235 family 3 1
5-hydroxytryptamine receptor 4 ligand AGN-PC-087VMU family 1 4
D(2) dopamine receptor ligand 2-chloro-3-ethyl-N-[[(2S)-1-ethy... 3 0
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Prelamin-A/C and Cruzipain inhibitor CHEMBL1598118 family 1 3
Prothrombin inhibitor AGN-PC-09QMX5 family 2 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 6
5-hydroxytryptamine receptor 4 ligand AGN-PC-01LVA9 family 3 11
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Histamine H3 receptor and Sodium-dependent serotonin transport... 14 3
5-hydroxytryptamine receptor 4 ligand AGN-PC-00GPBT family 2 3


External ID

Functional Category

Molecule Name

CFAMM00157561 CHEMBL327798 Bioactive 4-amino-5-chloro-N-(3-piperidin-1-ylpropyl)-2,3-dihydro-1-benzofuran-7-carboxamide
CFAMM00157552 CHEMBL91842 Bioactive AGN-PC-072PVG
CFAMM00157566 CHEMBL315071 Bioactive SureCN7360905
CFAMM00157553 DCL000854 Clinical Trial Drug KB-6806
CFAMM00157562 DNC001155 Investigative Drug Prucalopride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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