CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFCD442
Family Name Voltage-gated sodium channel Ligand Lacosamide Family
No. of Seeds 1 No. of Other Members 10
Family Centroid CFAMM00157576 Functional Category Clinical Trial Drug with Human Metabolite & Natural Product
Superfamily Voltage-gated sodium channel Ligand Lacosamide Superfamily
Class Class 260

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Mephenytoin... 5 51
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Acetylcholinesterase Inhibitor Ambenonium Family 4 71
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Aminopeptidase N Inhibitor 2-amino-n1-benzyl-n3-hydroxymalonam... 3 4
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Cathepsin S inhibitor SureCN7062841 family 7 7
Cathepsin K and Cathepsin S inhibitor 1-benzyl-3-[(2S)-1-[[cya... 1 0
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor Su... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00157576 DCL000858 Clinical Trial Drug Lacosamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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